Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PBD-150 is an inhibitor of human glutaminyl cyclase (hQC) Y115E-Y117E variant( ki : 490 nM)
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 51.00 | |
2 mg | In stock | $ 74.00 | |
5 mg | In stock | $ 122.00 | |
10 mg | In stock | $ 226.00 | |
25 mg | In stock | $ 397.00 | |
50 mg | In stock | $ 589.00 | |
100 mg | In stock | $ 843.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 133.00 |
Description | PBD-150 is an inhibitor of human glutaminyl cyclase (hQC) Y115E-Y117E variant( ki : 490 nM) |
In vivo | A glutaminyl cyclase (QC) inhibitor, PBD150, was shown to be able to reduce the deposition of pyroglutamate-modified amyloid-β peptides in brain of transgenic mouse models of Alzheimer disease, leading to a significant improvement of learning and memory in those transgenic animals[1]. |
Molecular Weight | 320.41 |
Formula | C15H20N4O2S |
CAS No. | 790663-33-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 125 mg/mL (390.13 mM), sonification is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
PBD-150 790663-33-1 Neuroscience Beta Amyloid Inhibitor Amyloid-β Abeta β-amyloid peptide inhibit Alzheimer PBD 150 PBD150 inhibitor