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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $52 | In Stock | |
10 mg | $85 | In Stock | |
25 mg | $166 | In Stock | |
50 mg | $247 | In Stock | |
100 mg | $369 | In Stock | |
200 mg | $553 | In Stock | |
500 mg | $892 | In Stock | |
1 mL x 10 mM (in DMSO) | $58 | In Stock |
Description | PRL-3 Inhibitor I (BR-1) is a phosphatase of regenerating liver 3 (PRL-3) inhibitor which blocks the migration and invasion of metastatic cancer cells. |
Targets&IC50 | PRL3:0.9 μM (IC50) |
In vitro | PRL-3 inhibitor, in a dose-dependent fashion, blocked the dephosphorylation of DiFMUP by PRL-3 and strongly suppressed the activity of PRL-3 phosphatase in PRL-3 overexpressing DLD-1 colon tumor cells [DLD-1 (PRL-3)]. Also, PRL-3 inhibitor dose-dependently blocked the migration of DLD-1 (PRL-3) cells, however, it did not inhibit the proliferation of DLD-1(PRL-3) cells, suggesting that PRL-3 inhibitor significantly blocked cell immigration and invasion without cytotoxicity |
Alias | PRL-3 Inhibitor, BR-1 |
Molecular Weight | 485.21 |
Formula | C17H11Br2NO2S2 |
Cas No. | 893449-38-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 55 mg/mL (113.35 mM) ![]() | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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