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PRL-3 Inhibitor I
🥰Excellent
Catalog No. T22136Cas No. 893449-38-2
Alias PRL-3 Inhibitor, BR-1
PRL-3 Inhibitor I (BR-1) is a phosphatase of regenerating liver 3 (PRL-3) inhibitor which blocks the migration and invasion of metastatic cancer cells.
PRL-3 Inhibitor I
🥰Excellent
Purity: 100%
Catalog No. T22136Alias PRL-3 Inhibitor, BR-1Cas No. 893449-38-2
PRL-3 Inhibitor I (BR-1) is a phosphatase of regenerating liver 3 (PRL-3) inhibitor which blocks the migration and invasion of metastatic cancer cells.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $29 | In Stock | |
| 10 mg | $49 | In Stock | |
| 25 mg | $98 | In Stock | |
| 50 mg | $148 | In Stock | |
| 100 mg | $221 | In Stock | |
| 200 mg | $332 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $35 | In Stock |
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Purity:100%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | PRL-3 Inhibitor I (BR-1) is a phosphatase of regenerating liver 3 (PRL-3) inhibitor which blocks the migration and invasion of metastatic cancer cells. |
| Targets&IC50 | PRL3:0.9 μM (IC50) |
| In vitro | PRL-3 inhibitor, in a dose-dependent fashion, blocked the dephosphorylation of DiFMUP by PRL-3 and strongly suppressed the activity of PRL-3 phosphatase in PRL-3 overexpressing DLD-1 colon tumor cells [DLD-1 (PRL-3)]. Also, PRL-3 inhibitor dose-dependently blocked the migration of DLD-1 (PRL-3) cells, however, it did not inhibit the proliferation of DLD-1(PRL-3) cells, suggesting that PRL-3 inhibitor significantly blocked cell immigration and invasion without cytotoxicity |
| Alias | PRL-3 Inhibitor, BR-1 |
| Molecular Weight | 485.21 |
| Formula | C17H11Br2NO2S2 |
| Cas No. | 893449-38-2 |
| Smiles | Brc1ccc(OCc2ccccc2Br)c(\C=C2/SC(=S)NC2=O)c1 |
| Relative Density. | 1.85 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 55 mg/mL (113.35 mM)  | |||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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