Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PRT4165 (NSC600157) is a potent PRC1-mediated H2A ubiquitylation inhibitor.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 38.00 | |
10 mg | In stock | $ 47.00 | |
25 mg | In stock | $ 85.00 | |
50 mg | In stock | $ 121.00 | |
100 mg | In stock | $ 202.00 | |
200 mg | In stock | $ 282.00 | |
500 mg | In stock | $ 475.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 45.00 |
Description | PRT4165 (NSC600157) is a potent PRC1-mediated H2A ubiquitylation inhibitor. |
Targets&IC50 | RING1A-BMI1:3.9 μM |
In vitro | Inhibit the?in vitro?E3 ubiquitin ligase activity of RNF2 and a Bmi1/RNF2 complex and H2A/H2AX ubiquitination |
In vivo | Blocks polycomb repressor complex (PRC) 1-mediated histone H2A ubiquitination?in vitro?and?in vivo. |
Synonyms | NSC600157, PRT 4165 |
Molecular Weight | 235.24 |
Formula | C15H9NO2 |
CAS No. | 31083-55-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 23.5 mg/mL(100 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
PRT4165 31083-55-3 Cell Cycle/Checkpoint DNA Damage/DNA Repair Others Ubiquitination BMI-1 E1/E2/E3 Enzyme E1 activating enzyme NSC-600157 NSC600157 PRT-4165 E3 ligating enzyme Ubiquitin ligase E2 conjugating enzyme PRT 4165 NSC 600157 inhibit Inhibitor Ubiquitin conjugating enzyme Ubiquitin activating enzyme inhibitor