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Pim1/AKK1-IN-1
🥰Excellent
Catalog No. T5093Cas No. 1093222-27-5
Alias MDK-2275, LKB1/AAK1 dual inhibitor
Pim1/AKK1-IN-1 (LKB1/AAK1 dual inhibitor) is a potent multi-kinase inhibitor with Kd values of 35 nM/53 nM/75 nM/380 nM for Pim1/AKK1/MST2/LKB1 respectively, and also inhibits MPSK1 and TNIK.
Pim1/AKK1-IN-1
🥰Excellent
Purity: 98.69%
Catalog No. T5093Alias MDK-2275, LKB1/AAK1 dual inhibitorCas No. 1093222-27-5
Pim1/AKK1-IN-1 (LKB1/AAK1 dual inhibitor) is a potent multi-kinase inhibitor with Kd values of 35 nM/53 nM/75 nM/380 nM for Pim1/AKK1/MST2/LKB1 respectively, and also inhibits MPSK1 and TNIK.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $82 | In Stock | |
| 2 mg | $133 | In Stock | |
| 5 mg | $193 | In Stock | |
| 10 mg | $292 | In Stock | |
| 25 mg | $515 | In Stock | |
| 50 mg | $747 | In Stock | |
| 100 mg | $1,050 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $213 | In Stock |
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Purity:98.69%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Pim1/AKK1-IN-1 (LKB1/AAK1 dual inhibitor) is a potent multi-kinase inhibitor with Kd values of 35 nM/53 nM/75 nM/380 nM for Pim1/AKK1/MST2/LKB1 respectively, and also inhibits MPSK1 and TNIK. |
| Targets&IC50 | MST2:75 nM (Kd), AKK1:53 nM (Kd), Pim1:35 nM (Kd), LKB1:380 nM (Kd) |
| Alias | MDK-2275, LKB1/AAK1 dual inhibitor |
| Molecular Weight | 339.35 |
| Formula | C20H13N5O |
| Cas No. | 1093222-27-5 |
| Smiles | O=C(Nc1c[nH]c2ncc(cc12)-c1ccc(cc1)C#N)c1cccnc1 |
| Relative Density. | 1.42 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 15 mg/mL (44.2 mM)  | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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