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Pomalidomide-PEG4-C-COOH

🥰Excellent
Catalog No. T17325Cas No. 2097938-44-6
Alias E3 Ligase Ligand-Linker Conjugates 1, Cereblon Ligand -Linker Conjugates 1

Pomalidomide-PEG4-C-COOH (E3 Ligase Ligand-Linker Conjugates 1) is a synthesized E3 ligase ligand-linker conjugate that combines the Pomalidomide-based cereblon ligand and 4-unit PEG linker used in PROTAC technology.

Pomalidomide-PEG4-C-COOH

Pomalidomide-PEG4-C-COOH

🥰Excellent
Purity: 96%
Catalog No. T17325Alias E3 Ligase Ligand-Linker Conjugates 1, Cereblon Ligand -Linker Conjugates 1Cas No. 2097938-44-6
Pomalidomide-PEG4-C-COOH (E3 Ligase Ligand-Linker Conjugates 1) is a synthesized E3 ligase ligand-linker conjugate that combines the Pomalidomide-based cereblon ligand and 4-unit PEG linker used in PROTAC technology.
Pack SizePriceAvailabilityQuantity
1 mg$36In Stock
5 mg$84In Stock
10 mg$122In Stock
25 mg$198In Stock
50 mg$297In Stock
100 mg$455In Stock
200 mg$783In Stock
1 mL x 10 mM (in DMSO)$109In Stock
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Purity:96%
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Product Introduction

Bioactivity
Description
Pomalidomide-PEG4-C-COOH (E3 Ligase Ligand-Linker Conjugates 1) is a synthesized E3 ligase ligand-linker conjugate that combines the Pomalidomide-based cereblon ligand and 4-unit PEG linker used in PROTAC technology.
AliasE3 Ligase Ligand-Linker Conjugates 1, Cereblon Ligand -Linker Conjugates 1
Chemical Properties
Molecular Weight507.49
FormulaC23H29N3O10
Cas No.2097938-44-6
SmilesO=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2NCCOCCOCCOCCOCC(O)=O
Relative Density.1.410 g/cm3 (Predicted)
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: 25 mg/mL (49.26 mM), Sonication is recommended.
DMSO: 50 mg/mL (98.52 mM), Sonication is recommended.
Solution Preparation Table
Ethanol/DMSO
1mg5mg10mg50mg
1 mM1.9705 mL9.8524 mL19.7048 mL98.5241 mL
5 mM0.3941 mL1.9705 mL3.9410 mL19.7048 mL
10 mM0.1970 mL0.9852 mL1.9705 mL9.8524 mL
20 mM0.0985 mL0.4926 mL0.9852 mL4.9262 mL
DMSO
1mg5mg10mg50mg
50 mM0.0394 mL0.1970 mL0.3941 mL1.9705 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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