Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SJFα is a 13-atom linker PROTAC. SJFα degrades p38α with a DC50 of 7.16 nM, but is far less effective at degrading p38δ (DC50=299 nM) and does not degrade the other p38 isoforms (β and γ) at concentrations up to 2.5 μM[1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | 4-5 weeks | $ 735.00 |
Description | SJFα is a 13-atom linker PROTAC. SJFα degrades p38α with a DC50 of 7.16 nM, but is far less effective at degrading p38δ (DC50=299 nM) and does not degrade the other p38 isoforms (β and γ) at concentrations up to 2.5 μM[1]. |
Targets&IC50 | p38α:7.16 nM (DC50), p38δ:299 nM (DC50) |
Molecular Weight | 1120.27 |
Formula | C59H67F2N7O11S |
CAS No. | 2254609-27-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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SJFα 2254609-27-1 Others SJFalpha SJFa inhibitor inhibit