Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Substance P(1-7) (Substance P 1-7) is the major bioactive metabolite formed after proteolytic degradation of the tachykinin substance P (SP),with anti-inflammatory, anti-nociceptive and anti-hyperalgesic effects
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2 mg | Inquiry | $ 70.00 | |
5 mg | Inquiry | $ 98.00 | |
10 mg | Inquiry | $ 160.00 | |
25 mg | Inquiry | $ 288.00 | |
50 mg | Inquiry | $ 432.00 | |
100 mg | Inquiry | $ 648.00 |
Description | Substance P(1-7) (Substance P 1-7) is the major bioactive metabolite formed after proteolytic degradation of the tachykinin substance P (SP),with anti-inflammatory, anti-nociceptive and anti-hyperalgesic effects |
In vivo | Substance P 1-7, SP(1-7), which is the main SP fragment in rat CNS, was injected intranigrally. SP(1-7) was found to act as a very potent antagonist against the SP-induced responses and was formed locally in the nigra after SP injection. It is proposed that SP(1-7) is an endogenous modulator of SP actions. Generation of peptide fragments, which retain receptor affinity but not efficacy, may be a general mechanism for autoregulation in peptidergic systems[1]. |
Synonyms | Substance P 1-7 |
Molecular Weight | 900.04 |
Formula | C41H65N13O10 |
CAS No. | 68060-49-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Substance P(1-7) 68060-49-1 GPCR/G Protein Neuroscience Others Neurokinin receptor Substance P(1 7) Inhibitor Substance P Tachykinin receptor Substance P 1-7 inhibit NK receptor Neurokinin Receptor Substance P(17) inhibitor