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VPC171

Catalog No. T29112Cas No. 1018830-99-3
Alias VPC-171, VPC 171

VPC171 is a novel adenosine A1 receptor positive allosteric modulator (PAM).

VPC171

VPC171

Purity: 99.52%
Catalog No. T29112Alias VPC-171, VPC 171Cas No. 1018830-99-3
VPC171 is a novel adenosine A1 receptor positive allosteric modulator (PAM).
Pack SizePriceAvailabilityQuantity
1 mg$67In Stock
2 mg$88In Stock
5 mg$133In Stock
10 mg$191In Stock
25 mg$353In Stock
50 mg$492In Stock
100 mg$696In Stock
200 mg$938In Stock
1 mL x 10 mM (in DMSO)$136In Stock
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Purity:99.52%
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Product Introduction

Bioactivity
Description
VPC171 is a novel adenosine A1 receptor positive allosteric modulator (PAM).
In vivo
VCP171 produced a greater inhibition of eEPSC amplitude of nerve-injury versus control animals in both lamina I and lamina II neurons[2].
AliasVPC-171, VPC 171
Chemical Properties
Molecular Weight347.35
FormulaC18H12F3NOS
Cas No.1018830-99-3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 55 mg/mL (158.34 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.8789 mL14.3947 mL28.7894 mL143.9470 mL
5 mM0.5758 mL2.8789 mL5.7579 mL28.7894 mL
10 mM0.2879 mL1.4395 mL2.8789 mL14.3947 mL
20 mM0.1439 mL0.7197 mL1.4395 mL7.1974 mL
50 mM0.0576 mL0.2879 mL0.5758 mL2.8789 mL
100 mM0.0288 mL0.1439 mL0.2879 mL1.4395 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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