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VPC171

VPC171
VPC171 is a novel adenosine A1 receptor positive allosteric modulator (PAM).
Catalog No. T29112Cas No. 1018830-99-3
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Purity:99.52%
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VPC171

Purity: 99.52%
Catalog No. T29112Alias VPC-171, VPC 171Cas No. 1018830-99-3

VPC171 is a novel adenosine A1 receptor positive allosteric modulator (PAM).
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
1 mg$67In Stock
2 mg$88In Stock
5 mg$133In Stock
10 mg$191In Stock
25 mg$353In Stock
50 mg$492In Stock
100 mg$696In Stock
200 mg$938In Stock
1 mL x 10 mM (in DMSO)$136In Stock
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Product Introduction

Bioactivity
Description
VPC171 is a novel adenosine A1 receptor positive allosteric modulator (PAM).
In vivo
VCP171 produced a greater inhibition of eEPSC amplitude of nerve-injury versus control animals in both lamina I and lamina II neurons[2].
AliasVPC-171, VPC 171
Chemical Properties
Molecular Weight347.35
FormulaC18H12F3NOS
Cas No.1018830-99-3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 55 mg/mL (158.34 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.8789 mL14.3947 mL28.7894 mL143.9470 mL
5 mM0.5758 mL2.8789 mL5.7579 mL28.7894 mL
10 mM0.2879 mL1.4395 mL2.8789 mL14.3947 mL
20 mM0.1439 mL0.7197 mL1.4395 mL7.1974 mL
50 mM0.0576 mL0.2879 mL0.5758 mL2.8789 mL
100 mM0.0288 mL0.1439 mL0.2879 mL1.4395 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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