Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Valiglurax (VU2957), also known as VU0652957 and VU2957, is a potent, selective, CNS penetrant, and orally bioavailable mGlu4 PAM. VU2957 possessed attractive in vitro and in vivo pharmacological and DMPK properties across species. VU2957 was evaluated as a preclinical development candidate for the treatment of Parkinson’s disease.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 31.00 | |
5 mg | In stock | $ 72.00 | |
10 mg | In stock | $ 122.00 | |
25 mg | In stock | $ 263.00 | |
50 mg | In stock | $ 449.00 | |
100 mg | In stock | $ 667.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 79.00 |
Description | Valiglurax (VU2957), also known as VU0652957 and VU2957, is a potent, selective, CNS penetrant, and orally bioavailable mGlu4 PAM. VU2957 possessed attractive in vitro and in vivo pharmacological and DMPK properties across species. VU2957 was evaluated as a preclinical development candidate for the treatment of Parkinson’s disease. |
In vivo | Valiglurax (0.3-30 mg/kg; po) reversed haloperidol-induced catalepsy (HIC) in rats[1]. |
Synonyms | VU2957, VU 0652957, VU 2957, VU-0652957, VU0652957, VU-2957 |
Molecular Weight | 329.28 |
Formula | C16H10F3N5 |
CAS No. | 1976050-09-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 112.5 mg/mL (341.7 mM), Sonification is recommended.
You can also refer to dose conversion for different animals. More
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Valiglurax 1976050-09-5 Neuroscience GluR VU2957 VU 0652957 VU 2957 VU-0652957 VU0652957 VU-2957 inhibitor inhibit