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Vitamin D3

Catalog No. T1135Cas No. 67-97-0
Alias Colecalciferol, Cholecalciferol

Vitamin D3 (Cholecalciferol) , a naturally occurring form of vitamin D, activates an H305F/H397Y mutant vitamin D receptor (VDR).

Vitamin D3

Vitamin D3

Purity: 99.82%
Catalog No. T1135Alias Colecalciferol, CholecalciferolCas No. 67-97-0
Vitamin D3 (Cholecalciferol) , a naturally occurring form of vitamin D, activates an H305F/H397Y mutant vitamin D receptor (VDR).
Pack SizePriceAvailabilityQuantity
1 g$33In Stock
1 mL x 10 mM (in DMSO)$39In Stock
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Purity:99.82%
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Product Introduction

Bioactivity
Description
Vitamin D3 (Cholecalciferol) , a naturally occurring form of vitamin D, activates an H305F/H397Y mutant vitamin D receptor (VDR).
Targets&IC50
H305F/H397Y mutant vitamin D receptor:300 nM(Kd)
AliasColecalciferol, Cholecalciferol
Chemical Properties
Molecular Weight384.64
FormulaC27H44O
Cas No.67-97-0
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 45 mg/mL (116.99 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5998 mL12.9992 mL25.9983 mL129.9917 mL
5 mM0.5200 mL2.5998 mL5.1997 mL25.9983 mL
10 mM0.2600 mL1.2999 mL2.5998 mL12.9992 mL
20 mM0.1300 mL0.6500 mL1.2999 mL6.4996 mL
50 mM0.0520 mL0.2600 mL0.5200 mL2.5998 mL
100 mM0.0260 mL0.1300 mL0.2600 mL1.2999 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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%
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Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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