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Aflatoxin G1
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Catalog No. TN1359Cas No. 1165-39-5
Aflatoxin G1 is a mycotoxin produced by Aspergillus flavus and Aspergillus parasiticus, which is hepatotoxic, teratogenic, immunosuppressive, and carcinogenic, and is mainly found in contaminated cereals. Aflatoxin G1 inhibits RNA polymerase activity, affects RNA and protein synthesis, and causes damage to the liver and kidney.
Aflatoxin G1
😃Good
Catalog No. TN1359Cas No. 1165-39-5
Aflatoxin G1 is a mycotoxin produced by Aspergillus flavus and Aspergillus parasiticus, which is hepatotoxic, teratogenic, immunosuppressive, and carcinogenic, and is mainly found in contaminated cereals. Aflatoxin G1 inhibits RNA polymerase activity, affects RNA and protein synthesis, and causes damage to the liver and kidney.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $232 | 7-10 days | |
| 1 mL x 10 mM (in DMSO) | $600 | 7-10 days |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Aflatoxin G1 is a mycotoxin produced by Aspergillus flavus and Aspergillus parasiticus, which is hepatotoxic, teratogenic, immunosuppressive, and carcinogenic, and is mainly found in contaminated cereals. Aflatoxin G1 inhibits RNA polymerase activity, affects RNA and protein synthesis, and causes damage to the liver and kidney. |
| In vitro | Aflatoxin G1 was removed from liquid cultures by growing and resting cells of Flavobacterium aurantiacum NRRL B-184. In inoculated culture media containing toxin levels of 7.5 p.p.m. and above, there was a protracted growth lag which was subsequently overcome; toxin removal then occurred, concomitant with growth. Only a few cells demonstrated aberrant morphological forms when cultured in the presence of Aflatoxin G1. A comparison of the effects of Aflatoxin G1 with B1 on growth and morphology showed that B1 was distinctly more toxic[1] |
| Molecular Weight | 328.27 |
| Formula | C17H12O7 |
| Cas No. | 1165-39-5 |
| Smiles | O(C)C=1C2=C(C3=C(O[C@@]4([C@]3(C=CO4)[H])[H])C1)OC(=O)C5=C2CCOC5=O |
| Relative Density. | 1.3358 g/cm3 (Estimated) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 8 mg/mL (24.37 mM), Sonication is recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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