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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $39 | In Stock | |
10 mg | $67 | In Stock | |
25 mg | $138 | In Stock | |
50 mg | $222 | In Stock | |
100 mg | $328 | In Stock | |
1 mL x 10 mM (in DMSO) | $43 | In Stock |
Description | AM 374 (HDSF), a fatty acid amide hydrolase (FAAH) inhibitor, demonstrates the capacity to inhibit amidase activity, boasting an IC50 value of 13 nM. This compound is potentially applicable in neurological disease research. |
Targets&IC50 | Amidase:13 nM |
In vitro | AM 374 (0-9 nM) inhibits anandamide degradation in N18TG2 cells. [1] |
In vivo | AM 374 (20 μg ; intraventricular injection, once) has no effect on lever pressing in FR5, but when used in combination with anandamide (intraperitoneal injection), it reduces lever pressing.[2] |
Alias | HDSF, Hexadecanesulfonyl fluoride |
Molecular Weight | 308.5 |
Formula | C16H33FO2S |
Cas No. | 86855-26-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 90.0 mg/mL (291.7 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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