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AMTB hydrochloride
🥰Excellent
Catalog No. T19723Cas No. 926023-82-7
Alias AMTB
AMTB hydrochloride (AMTB HCl) is a novel TRPM8 channel blocker and is effective for pain and urinary diseases. AMTB can act on the bladder afferent pathway to attenuate the bladder micturition reflex and nociceptive reflex responses in the rat.
AMTB hydrochloride
🥰Excellent
Purity: 99.08%
Catalog No. T19723Alias AMTBCas No. 926023-82-7
AMTB hydrochloride (AMTB HCl) is a novel TRPM8 channel blocker and is effective for pain and urinary diseases. AMTB can act on the bladder afferent pathway to attenuate the bladder micturition reflex and nociceptive reflex responses in the rat.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | 29 € | In Stock | |
| 2 mg | 41 € | In Stock | |
| 5 mg | 68 € | In Stock | |
| 10 mg | 121 € | In Stock | |
| 25 mg | 264 € | In Stock | |
| 50 mg | 448 € | In Stock | |
| 100 mg | 662 € | In Stock | |
| 500 mg | 1.396 € | In Stock | |
| 1 mL x 10 mM (in DMSO) | 86 € | In Stock |
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Purity:99.08%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | AMTB hydrochloride (AMTB HCl) is a novel TRPM8 channel blocker and is effective for pain and urinary diseases. AMTB can act on the bladder afferent pathway to attenuate the bladder micturition reflex and nociceptive reflex responses in the rat. |
| In vivo | For rats, AMTB (10 mg/kg) significantly attenuated reflex responses to noxious urinary bladder distension (UBD) to 5.42 and 56.51% of the maximal visceromotor reflex (VMR) response and pressor response, respectively. The ID50 value on VMR response was 2.42 +/- 0.46 mg/kg [1]. |
| Alias | AMTB |
| Molecular Weight | 430.99 |
| Formula | C23H27ClN2O2S |
| Cas No. | 926023-82-7 |
| Smiles | Cl.Cc1cccc(COc2ccccc2C(=O)N(CCCN)Cc2cccs2)c1 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 60 mg/ml (139.21 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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