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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $31 | In Stock | |
2 mg | $43 | In Stock | |
5 mg | $72 | In Stock | |
10 mg | $117 | In Stock | |
25 mg | $247 | In Stock | |
50 mg | $372 | In Stock | |
100 mg | $597 | In Stock | |
1 mL x 10 mM (in DMSO) | $98 | In Stock |
Description | AUZ 454 (K03861) is a type II CDK2 inhibitor with Kd of 50 nM, 18.6 nM, 15.4 nM, and 9.7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely. |
In vitro | K03861 inhibits CDK2 activity by competing with binding of activating cyclins. [1] |
Alias | K03861 |
Molecular Weight | 501.5 |
Formula | C24H26F3N7O2 |
Cas No. | 853299-07-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||||||||||||||||||||||
Solubility Information | Ethanol: 12 mg/mL (23.9 mM) DMSO: 93 mg/mL (185.4 mM) H2O: < 1 mg/mL (insoluble or slightly soluble) | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
DMSO/Ethanol
DMSO
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