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B7/CD28 interaction inhibitor 1

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Purity:99.5%

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COA HNMR HPLC

B7/CD28 interaction inhibitor 1

Catalog No. T3189Cas No. 635324-72-0

B7/CD28 interaction inhibitor 1 (CTLA-4 inhibitor) is a potent CTLA-4 inhibitor.

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Pack Size	Price	Availability
1 mg	$77	In Stock
2 mg	$115	In Stock
5 mg	$193	In Stock
10 mg	$313	In Stock
25 mg	$578	In Stock
50 mg	$828	In Stock
100 mg	$1,090	In Stock
1 mL x 10 mM (in DMSO)	$213	In Stock

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Product Introduction

Bioactivity

Description	B7/CD28 interaction inhibitor 1 (CTLA-4 inhibitor) is a potent CTLA-4 inhibitor.
Alias	CTLA-4 inhibitor

Chemical Properties

Molecular Weight	427.35
Formula	C21H13F4N5O
Cas No.	635324-72-0

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 85 mg/mL (198.90 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3400 mL	11.7000 mL	23.4000 mL	117.0001 mL
5 mM	0.4680 mL	2.3400 mL	4.6800 mL	23.4000 mL
10 mM	0.2340 mL	1.1700 mL	2.3400 mL	11.7000 mL
20 mM	0.1170 mL	0.5850 mL	1.1700 mL	5.8500 mL
50 mM	0.0468 mL	0.2340 mL	0.4680 mL	2.3400 mL
100 mM	0.0234 mL	0.1170 mL	0.2340 mL	1.1700 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc