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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $40 | In Stock | |
2 mg | $56 | In Stock | |
5 mg | $97 | In Stock | |
10 mg | $172 | In Stock | |
25 mg | $288 | In Stock | |
50 mg | $428 | In Stock | |
100 mg | $637 | In Stock | |
1 mL x 10 mM (in DMSO) | $98 | In Stock |
Description | Belvarafenib is a potent and pan RAF inhibitor with antineoplastic activity. The IC50 values of Belvarafenib are 56 nM, 7 nM and 5 nM for B-RAF, B-RAFv600E and C-RAF respectively. |
In vitro | Belvarafenib ?is a potent and pan RAF inhibitor with antineoplastic activity.?The IC50 values of Belvarafenib are 56 nM, 7 nM and 5 nM for B-RAF, B-RAFv600E and C-RAF respectively.?It also shows high inhibitory activity for FMS, DDR1 and DDR2 kinases, with IC50s of 10 nM, 23 nM and 44 nM, respectively. |
Molecular Weight | 478.93 |
Formula | C23H16ClFN6OS |
Cas No. | 1446113-23-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 25 mg/mL (52.2 mM) ![]() | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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