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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $89 | In Stock | |
5 mg | $196 | In Stock | |
10 mg | $322 | In Stock | |
25 mg | $645 | In Stock | |
50 mg | $987 | In Stock | |
100 mg | $1,330 | In Stock | |
500 mg | $2,670 | In Stock | |
1 mL x 10 mM (in DMSO) | $263 | In Stock |
Description | BMS CCR2 22 is a potent and selective antagonist of CCR2 with calcium flux IC50 of 18 nM, chemotaxis IC50 of 1 nM, and binding IC50 of 5.1 nM. |
In vitro | BMS CCR2 22 inhibits the internalization of hMCP1_AF647 (IC50 = 2 nM)[2]. HAoECs with BMS CCR2 22 before MCP-1 increases the cell surface levels of VCAM-1 from 72.8 to 160% and PECAM1 from 97.2 and 127%[3]. |
Molecular Weight | 593.66 |
Formula | C28H34F3N5O4S |
Cas No. | 445479-97-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 225.0 mg/mL (379.0 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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