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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $31 | In Stock | |
5 mg | $72 | In Stock | |
10 mg | $122 | In Stock | |
25 mg | $198 | In Stock | |
50 mg | $297 | In Stock | |
100 mg | $453 | In Stock | |
1 mL x 10 mM (in DMSO) | $86 | In Stock |
Description | CB2R/FAAH modulator-2 (compound 26) is a dual modulator targeting at CB2R and FAAH. CB2R/FAAH modulator-2 acts as a CB2R agonist and FAAH inhibitor, the Ki values are 10.8 and 152.9 nM for CB2R and CB1R, respectively, and the IC50 value for FAAH is 6.2 μM. CB2R/FAAH modulator-2 has studies research value related to cancer, deleterious inflammatory cascades occurring in neurodegenerative diseases, and COVID-19 infection. |
In vitro | CB2R/FAAH modulator-2 (compound 26)(10 μ M) can reduce the production of pro-inflammatory cytokine TNF α、 IFN- γ、 IL-1 β and IL6 in unstimulated monocytes and macrophages[1]. |
Molecular Weight | 367.52 |
Formula | C24H33NO2 |
Cas No. | 2876918-68-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||
Solubility Information | DMSO: 3.68 mg/mL (10 mM) | |||||||||||||||
Solution Preparation Table | ||||||||||||||||
DMSO
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