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CFTR corrector 12

TargetMol
Catalog No. T79578Cas No. 958941-60-1

CFTR corrector 12 is a CFTR corrector that rescues all mutant proteins except M760R ABCA3, and can be used to study cystic fibrosis.

CFTR corrector 12

CFTR corrector 12

TargetMol
Purity: 99.78%
Catalog No. T79578Cas No. 958941-60-1
CFTR corrector 12 is a CFTR corrector that rescues all mutant proteins except M760R ABCA3, and can be used to study cystic fibrosis.
Pack SizePriceAvailabilityQuantity
1 mg$176In Stock
5 mg$455In Stock
10 mg$645In Stock
25 mg$987In Stock
50 mg$1,380In Stock
100 mg$1,870In Stock
200 mg$2,520In Stock
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Purity:99.78%
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Product Introduction

Bioactivity
Description
CFTR corrector 12 is a CFTR corrector that rescues all mutant proteins except M760R ABCA3, and can be used to study cystic fibrosis.
In vitro
The CFTR corrector 12 , when applied at a concentration of 15 μM for 72 hours, is capable of restoring α-sarcoglycan levels in cells harboring the L31P/V247M α-SG mutations[1].
Chemical Properties
Molecular Weight436.98
FormulaC19H21ClN4O2S2
Cas No.958941-60-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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