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Docosahexaenoic Acid
🥰Excellent
Catalog No. T5369Cas No. 6217-54-5
Alias DHA, Cervonic acid
Docosahexaenoic Acid (DHA) is an essential omega-3 fatty acid prevalent in the brain and retina.
Docosahexaenoic Acid
🥰Excellent
Purity: 99.71%
Catalog No. T5369Alias DHA, Cervonic acidCas No. 6217-54-5
Docosahexaenoic Acid (DHA) is an essential omega-3 fatty acid prevalent in the brain and retina.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 mg | $34 | In Stock | |
| 100 mg | $50 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $50 | In Stock |
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Purity:99.71%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Docosahexaenoic Acid (DHA) is an essential omega-3 fatty acid prevalent in the brain and retina. |
| In vitro | When monocytes were differentiated to dendritic cells (DCs) in the presence of docosahexaenoic acid (DHA), the expression of costimulatory and antigen presentation markers was altered in a concentration-dependent way, positively or negatively, depending on the markers tested and the maturation stage of the DCs. DHA-treated, mature DCs showed inhibition of IL-6 expression and IL-10 and IL-12 secretion, and their lymphoproliferative stimulation capacity was impaired [1]. |
| In vivo | An experimental model of PD was created by four intraperitoneal injections of MPTP (4 × 20 mg/kg, at 12h intervals). Docosahexaenoic acid was given daily by gavage for 4 weeks (36 mg/kg/day). The number of apoptotic dopaminergic cells significantly increased in MPTP-treated mice compared to controls. Although DHA significantly diminished the number of cell deaths in MPTP-treated mice, it did not improve the decreased motor activity observed in the experimental PD model. Docosahexaenoic acid significantly diminished the amount of cell death in the MPTP+DHA group as compared to the MPTP group [2]. |
| Alias | DHA, Cervonic acid |
| Molecular Weight | 328.49 |
| Formula | C22H32O2 |
| Cas No. | 6217-54-5 |
| Smiles | CCC=CCC=CCC=CCC=CCC=CCC=CCCC(O)=O |
| Relative Density. | 0.943 g/cm3 |
Storage & Solubility Information
| Storage | store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||||||||||||
| Solubility Information | Ethanol: 30 mg/mL (91.33 mM), Sonication is recommended. DMSO: 100 mg/mL (304.42 mM), Sonication is recommended.  H2O: 5 mg/mL (15.22 mM) | |||||||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||||||||||||
H2O/Ethanol/DMSO
Ethanol/DMSO
DMSO
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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