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FLT3-IN-10

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Purity:99.60%

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COA HNMR HPLC

FLT3-IN-10

Catalog No. T9856Cas No. 2088735-51-5

FLT3-IN-10 (2-Oxazolamine, 5-(4-fluorophenyl)-N-phenyl-) (compound 7c) is a potent inhibitor of FMS-like tyrosine kinase 3 (FLT3). FLT3-IN-10 shows the potential for the treatment of FLT3-mutated acute myeloid leukemia (AML).

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Pack Size	Price	Availability
1 mg	$54	In Stock
5 mg	$128	In Stock
10 mg	$222	In Stock
25 mg	$455	In Stock
50 mg	$672	In Stock
100 mg	$956	In Stock
500 mg	$1,920	In Stock
1 mL x 10 mM (in DMSO)	$123	In Stock

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Product Introduction

Bioactivity

Description	FLT3-IN-10 (2-Oxazolamine, 5-(4-fluorophenyl)-N-phenyl-) (compound 7c) is a potent inhibitor of FMS-like tyrosine kinase 3 (FLT3). FLT3-IN-10 shows the potential for the treatment of FLT3-mutated acute myeloid leukemia (AML).
Alias	2-Oxazolamine, 5-(4-fluorophenyl)-N-phenyl-

Chemical Properties

Molecular Weight	254.26
Formula	C15H11FN2O
Cas No.	2088735-51-5

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 55 mg/mL (216.31 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.9330 mL	19.6649 mL	39.3298 mL	196.6491 mL
5 mM	0.7866 mL	3.9330 mL	7.8660 mL	39.3298 mL
10 mM	0.3933 mL	1.9665 mL	3.9330 mL	19.6649 mL
20 mM	0.1966 mL	0.9832 mL	1.9665 mL	9.8325 mL
50 mM	0.0787 mL	0.3933 mL	0.7866 mL	3.9330 mL
100 mM	0.0393 mL	0.1966 mL	0.3933 mL	1.9665 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc