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FT011

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Purity:98%

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COA HNMR

FT011

Catalog No. T7298Cas No. 1001288-58-9

FT011, a direct anti-fibrotic agent,attenuates cardiac remodelling and dysfunction in experimental diabetic cardiomyopathy.

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Pack Size	Price	Availability
5 mg	$39	In Stock
10 mg	$64	In Stock
25 mg	$123	In Stock
50 mg	$228	In Stock
100 mg	$372	In Stock
200 mg	$517	In Stock
1 mL x 10 mM (in DMSO)	$43	In Stock

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Product Introduction

Bioactivity

Description	FT011, a direct anti-fibrotic agent,attenuates cardiac remodelling and dysfunction in experimental diabetic cardiomyopathy.
In vivo	A direct anti-fibrotic agent, FT011, attenuates cardiac remodelling and dysfunction in experimental diabetic cardiomyopathy[1].
Animal Research	Homozygous Ren-2 rats were randomized to receive streptozotocin or vehicle then further randomized to FT011 (200 mg/kg/day) or vehicle treatment for 6 weeks. Prior to tissue collection, cardiac function was assessed via echocardiography and cardiac catheterization. Total collagen deposition and cardiomyocyte hypertrophy were assessed by picrosirius red and haematoxylin and eosin staining, respectively. Macrophage interstitial infiltration and type I and III collagen were quantitated by immunostaining[1].

Chemical Properties

Molecular Weight	351.35
Formula	C20H17NO5
Cas No.	1001288-58-9

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 29 mg/mL (82.54 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8462 mL	14.2308 mL	28.4616 mL	142.3082 mL
5 mM	0.5692 mL	2.8462 mL	5.6923 mL	28.4616 mL
10 mM	0.2846 mL	1.4231 mL	2.8462 mL	14.2308 mL
20 mM	0.1423 mL	0.7115 mL	1.4231 mL	7.1154 mL
50 mM	0.0569 mL	0.2846 mL	0.5692 mL	2.8462 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

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