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Fumarate hydratase-IN-1

Fumarate hydratase-IN-1
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Purity:98.96%
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Fumarate hydratase-IN-1

Catalog No. T11337Cas No. 1644060-37-6
Fumarate hydratase-IN-1 is a cell-permeable fumarate hydratase inhibitor with antiproliferative activity and can be used to study cellular activity.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
1 mg$91In Stock
2 mg$131In Stock
5 mg$217In Stock
10 mg$317In Stock
25 mg$623In Stock
50 mg$973In Stock
100 mg$1,630In Stock
1 mL x 10 mM (in DMSO)$213In Stock
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Product Introduction

Bioactivity
Description
Fumarate hydratase-IN-1 is a cell-permeable fumarate hydratase inhibitor with antiproliferative activity and can be used to study cellular activity.
In vitro
Fumarate hydratase-IN-1 exhibits high sensitivity against cancer cell lines such as SW620, ACHN, HCT-116, inhibiting their proliferation with an average IC50 value of 2.2 μM[1].
Chemical Properties
Molecular Weight446.54
FormulaC27H30N2O4
Cas No.1644060-37-6
Storage & Solubility Information
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 30 mg/mL (67.18 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2394 mL11.1972 mL22.3944 mL111.9721 mL
5 mM0.4479 mL2.2394 mL4.4789 mL22.3944 mL
10 mM0.2239 mL1.1197 mL2.2394 mL11.1972 mL
20 mM0.1120 mL0.5599 mL1.1197 mL5.5986 mL
50 mM0.0448 mL0.2239 mL0.4479 mL2.2394 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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