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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $109 | In Stock | |
5 mg | $233 | In Stock | |
10 mg | $318 | In Stock | |
25 mg | $493 | In Stock | |
50 mg | $719 | In Stock | |
100 mg | $987 | In Stock | |
500 mg | $1,980 | In Stock | |
1 mL x 10 mM (in DMSO) | $216 | In Stock |
Description | GLP-26 disrupts the encapsidation of pre-genomic RNA, causes nucleocapsid disassembly and reduces cccDNA pools. GLP-26 is a HBV capsid assembly modulators (CAM), inhibits HBV DNA replication in Hep AD38 system (IC50=3 nM), and reduces cccDNA by >90% at 1 |
Targets&IC50 | HBV:3 nM, HBV:0.7 μM(EC50) |
In vitro | Administration of 0.7-1.7 μM GLP-26 for 3 days reduces secreted HBeAg in HepNTCP-DL cells transfected with HBV wild type with EC50 values of 0.7 μM[1]. |
Molecular Weight | 373.35 |
Formula | C19H17F2N3O3 |
Cas No. | 2133017-36-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 100 mg/mL (267.85 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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