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Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $148 | 5 days | |
5 mg | $247 | 7-10 days | |
10 mg | $413 | 7-10 days | |
1 mL x 10 mM (in DMSO) | $272 | 7-10 days |
Description | GW406108X (GW108X) is a Kif15 inhibitor with an IC50 of 0.82 uM in ATPase assays. GW406108X is also an ULK1 kinase inhibitor with pIC50 values of 6.37 (427 nM) and block autophagic flux. |
Targets&IC50 | KIF15:0.82 μM, ULK1:PIC50=6.37 |
In vitro | GW406108X were acting upon ULK1 and autophagy without affecting mTOR or AMPK activity as shown by monitoring ULK1 pS758 (mTOR site) or pS556 (AMPK site) levels[1]. |
Alias | GW108X |
Molecular Weight | 400.21 |
Formula | C20H11Cl2NO4 |
Cas No. | 1644443-92-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 45 mg/mL (112.44 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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