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Hexyl gallate (Gallic acid hexyl ester), an alkyl ester derivative of gallic acid, exhibits potent antimalarial activity against Plasmodium falciparum (IC50: 0.11 mM).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $31 | In Stock | |
50 mg | $44 | In Stock | |
100 mg | $64 | In Stock | |
200 mg | $109 | In Stock | |
500 mg | $183 | In Stock | |
1 mL x 10 mM (in DMSO) | $39 | In Stock |
Description | Hexyl gallate (Gallic acid hexyl ester), an alkyl ester derivative of gallic acid, exhibits potent antimalarial activity against Plasmodium falciparum (IC50: 0.11 mM). |
Targets&IC50 | Antimalarial:0.11 mM |
In vitro | Hexyl gallates (Hexyl 3,4,5-trihydroxybenzoate) selectively inhibit RhlR-dependent production of rhamnolipid and pyocyanin, impacting only Rhl-regulated pathways while preserving elastase production and biofilm formation controlled by the Las system. These compounds show pigment inhibition at concentrations of 10-30 μM and exhibit notable antibacterial properties. Hexyl gallates also suppress N-butanoyl homoserine lactone (BHL) production at 100 and 300 μM, without affecting N-(3-oxododecanoyl)-l-homoserine lactone (OdDHL) and 2-heptyl-3-hydroxy-4(1H) quinolone (PQS) synthesis. As a promising antimicrobial alternative to copper compounds, Hexyl gallates effectively inhibit Xanthomonas citri growth at 30-50 μg/ml by targeting the bacterium's membrane, demonstrating a dose-responsive behavior. |
Alias | Hexyl 3,4,5-trihydroxybenzoate, Gallic acid hexyl ester |
Molecular Weight | 254.28 |
Formula | C13H18O5 |
Cas No. | 1087-26-9 |
Smiles | CCCCCCOC(=O)c1cc(O)c(O)c(O)c1 |
Relative Density. | 1.239 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 50 mg/mL (196.63 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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