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Isatuximab
🥰Excellent
Catalog No. T38951Cas No. 1461640-62-9
Alias SAR-650984, Isatuximab-irfc, Isatuximab（anti-CD38）, hu38SB19
Isatuximab is a monoclonal antibody targeting the transmembrane receptor and extracellular enzyme CD38 in malignant cells of the hematological system, a highly expressed protein in multiple myeloma. It exhibits antitumor activity, antibody-dependent cytotoxicity, complement-dependent cytotoxicity, and antibody-dependent cytophagocytosis, directly inducing apoptosis without crosslinking. Isatuximab inhibits CD38 extracellular enzyme activity, affecting various cellular functions.
Isatuximab
🥰Excellent
Purity: 98.4% (SEC-HPLC)
Catalog No. T38951Alias SAR-650984, Isatuximab-irfc, Isatuximab（anti-CD38）, hu38SB19Cas No. 1461640-62-9
Isatuximab is a monoclonal antibody targeting the transmembrane receptor and extracellular enzyme CD38 in malignant cells of the hematological system, a highly expressed protein in multiple myeloma. It exhibits antitumor activity, antibody-dependent cytotoxicity, complement-dependent cytotoxicity, and antibody-dependent cytophagocytosis, directly inducing apoptosis without crosslinking. Isatuximab inhibits CD38 extracellular enzyme activity, affecting various cellular functions.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | 274 € | In Stock | |
| 5 mg | 678 € | In Stock | |
| 10 mg | 1.130 € | In Stock |
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Concentration:4.06 mg/mL
Purity:98.4% (SEC-HPLC)
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Isatuximab is a monoclonal antibody targeting the transmembrane receptor and extracellular enzyme CD38 in malignant cells of the hematological system, a highly expressed protein in multiple myeloma. It exhibits antitumor activity, antibody-dependent cytotoxicity, complement-dependent cytotoxicity, and antibody-dependent cytophagocytosis, directly inducing apoptosis without crosslinking. Isatuximab inhibits CD38 extracellular enzyme activity, affecting various cellular functions. |
| In vitro | The combination of Isatuximab with Pomalidomide (an immunomodulatory drug) results in greater direct toxicity and lysis of CD38 multiple myeloma cells by effector cells compared with Isatuximab alone [2] . |
| Alias | SAR-650984, Isatuximab-irfc, Isatuximab（anti-CD38）, hu38SB19 |
| Molecular Weight | 145.21 kDa |
| Cas No. | 1461640-62-9 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | store at low temperature | store at -20°C | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
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