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Isotrifoliin
🥰Excellent
Catalog No. T4902Cas No. 21637-25-2
Alias Isoquercitroside, Isoquercetin
Isotrifoliin (Isoquercitroside)n is an effective antioxidant and an eosinophilic inflammation suppressor.
Isotrifoliin
🥰Excellent
Purity: 99.45%
Catalog No. T4902Alias Isoquercitroside, IsoquercetinCas No. 21637-25-2
Isotrifoliin (Isoquercitroside)n is an effective antioxidant and an eosinophilic inflammation suppressor.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $29 | In Stock | |
| 10 mg | Inquiry | In Stock | |
| 1 mL x 10 mM (in DMSO) | $43 | In Stock |
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Purity:99.45%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Isotrifoliin (Isoquercitroside)n is an effective antioxidant and an eosinophilic inflammation suppressor. |
| In vitro | Isoquercitrin occurs widely in plants.10 μM of Isoquercitrin of the seven compounds partially but significantly blunt the negative effect of H2O2 on RGC-5 cells, as the viability of cells in the presence of H2O2 is increased from approximately 63% to 83% and 90% at 10 and 50 μM, respectively. Indeed, 50 μM Isoquercitrin is more effective as a neuroprotectant than the same concentration of EGCG. |
| In vivo | In animal studies, both Isoquercitrin and quercetin administration resulted in reduced eosinophil counts in the bronchoalveolar lavage fluid (BALF), blood, and lung parenchyma. Isoquercitrin-treated mice uniquely exhibited decreased neutrophil counts in blood and lower IL-5 concentrations in lung homogenates. No significant changes were observed in mononuclear cell counts. |
| Alias | Isoquercitroside, Isoquercetin |
| Molecular Weight | 464.38 |
| Formula | C21H20O12 |
| Cas No. | 21637-25-2 |
| Smiles | OC[C@@H](O)[C@H]1O[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)-c2ccc(O)c(O)c2)[C@H](O)[C@H]1O |
| Relative Density. | 1.87g/cm3 |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 125 mg/mL (269.18 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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