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KRAS G12C inhibitor 19

🥰Excellent
Catalog No. T40286Cas No. 2649788-46-3

KRAS G12C inhibitor 19 is a potent KRAS G12C inhibitor that demonstrates anti-tumor activity in cellular assays and inhibits tumor growth [1].

KRAS G12C inhibitor 19

KRAS G12C inhibitor 19

🥰Excellent
Purity: 98.31%
Catalog No. T40286Cas No. 2649788-46-3
KRAS G12C inhibitor 19 is a potent KRAS G12C inhibitor that demonstrates anti-tumor activity in cellular assays and inhibits tumor growth [1].
Pack SizePriceAvailabilityQuantity
1 mg$83In Stock
5 mg$196In Stock
10 mg$295In Stock
25 mg$572In Stock
50 mg$818In Stock
100 mg$1,130In Stock
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Purity:98.31%
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Product Introduction

Bioactivity
Description
KRAS G12C inhibitor 19 is a potent KRAS G12C inhibitor that demonstrates anti-tumor activity in cellular assays and inhibits tumor growth [1].
Chemical Properties
Molecular Weight528.96
FormulaC25H19ClF2N4O3S
Cas No.2649788-46-3
SmilesC(#N)C=1C2=C(C=CC(F)=C2SC1N)C=3C(Cl)=C4C(=CC3F)C(=O)N5[C@@](CCO4)(CN(C(C=C)=O)CC5)[H]
Storage & Solubility Information
Storagestore at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 52.90 mg/mL (100 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.8905 mL9.4525 mL18.9050 mL94.5251 mL
5 mM0.3781 mL1.8905 mL3.7810 mL18.9050 mL
10 mM0.1891 mL0.9453 mL1.8905 mL9.4525 mL
20 mM0.0945 mL0.4726 mL0.9453 mL4.7263 mL
50 mM0.0378 mL0.1891 mL0.3781 mL1.8905 mL
100 mM0.0189 mL0.0945 mL0.1891 mL0.9453 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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