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LY2979165

🥰Excellent
Catalog No. T15812Cas No. 1311385-32-6
Alias mGlu2 agonist

LY2979165 (mGlu2 agonist) is an orthosteric agonist of mGluR2 and can be used in studies about serving as an anti-depressant.

LY2979165

LY2979165

🥰Excellent
Purity: 100.00%
Catalog No. T15812Alias mGlu2 agonistCas No. 1311385-32-6
LY2979165 (mGlu2 agonist) is an orthosteric agonist of mGluR2 and can be used in studies about serving as an anti-depressant.
Pack SizePriceAvailabilityQuantity
1 mg$68In Stock
5 mg$156In Stock
10 mg$239In Stock
25 mg$395In Stock
50 mg$588In Stock
100 mg$838In Stock
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Purity:100.00%
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Product Introduction

Bioactivity
Description
LY2979165 (mGlu2 agonist) is an orthosteric agonist of mGluR2 and can be used in studies about serving as an anti-depressant.
In vivo
LY2979165 reduces BOLD signal and increases plasma levels of 2812223 in vivo[1].
AliasmGlu2 agonist
Chemical Properties
Molecular Weight390.42
FormulaC13H22N6O6S
Cas No.1311385-32-6
SmilesN.O.C[C@H](N)C(=O)N[C@]1(C[C@@H](Sc2ncn[nH]2)[C@H]2[C@@H]([C@@H]12)C(O)=O)C(O)=O
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 40 mg/mL (102.5 mM)
DMSO: 1 mg/mL (2.56 mM), Sonication and heating are recommended.
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM2.5613 mL12.8067 mL25.6134 mL128.0672 mL
H2O
1mg5mg10mg50mg
5 mM0.5123 mL2.5613 mL5.1227 mL25.6134 mL
10 mM0.2561 mL1.2807 mL2.5613 mL12.8067 mL
20 mM0.1281 mL0.6403 mL1.2807 mL6.4034 mL
50 mM0.0512 mL0.2561 mL0.5123 mL2.5613 mL
100 mM0.0256 mL0.1281 mL0.2561 mL1.2807 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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2 Enter the in vivo formulation:
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