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LY2979165

Catalog No. T15812Cas No. 1311385-32-6
Alias mGlu2 agonist

LY2979165 (mGlu2 agonist) is an orthosteric agonist of mGluR2 and can be used in studies about serving as an anti-depressant.

LY2979165

LY2979165

Purity: 100.00%
Catalog No. T15812Alias mGlu2 agonistCas No. 1311385-32-6
LY2979165 (mGlu2 agonist) is an orthosteric agonist of mGluR2 and can be used in studies about serving as an anti-depressant.
Pack SizePriceAvailabilityQuantity
1 mg$68In Stock
5 mg$156In Stock
10 mg$239In Stock
25 mg$395In Stock
50 mg$588In Stock
100 mg$838In Stock
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Purity:100.00%
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Product Introduction

Bioactivity
Description
LY2979165 (mGlu2 agonist) is an orthosteric agonist of mGluR2 and can be used in studies about serving as an anti-depressant.
In vivo
LY2979165 reduces BOLD signal and increases plasma levels of 2812223 in vivo[1].
AliasmGlu2 agonist
Chemical Properties
Molecular Weight390.42
FormulaC13H22N6O6S
Cas No.1311385-32-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 40 mg/mL (102.5 mM)
DMSO: 1 mg/mL (2.56 mM), Sonication and heating are recommended.
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM2.5613 mL12.8067 mL25.6134 mL128.0672 mL
H2O
1mg5mg10mg50mg
5 mM0.5123 mL2.5613 mL5.1227 mL25.6134 mL
10 mM0.2561 mL1.2807 mL2.5613 mL12.8067 mL
20 mM0.1281 mL0.6403 mL1.2807 mL6.4034 mL
50 mM0.0512 mL0.2561 mL0.5123 mL2.5613 mL
100 mM0.0256 mL0.1281 mL0.2561 mL1.2807 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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