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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $51 | In Stock | |
5 mg | $122 | In Stock | |
10 mg | $197 | In Stock | |
25 mg | $428 | In Stock | |
50 mg | $639 | In Stock | |
100 mg | $890 | In Stock | |
500 mg | $1,830 | In Stock |
Description | LY2389575 hydrochloride is an mGlu3 negative allosteric modulator (NAM) that is selective and non-competitive, with an IC50 value of 190 nM. LY2389575 hydrochloride induces an increase in the level of Mrc1, which amplifies the toxicity of β-amyloid (Aβ), and can be used to study Alzheimer's disease. It can be used to study Alzheimer's disease. |
In vitro | LY2389575 hydrochloride (5 μM; 1 h) Induce the increase of Mrc1 level in Microglial cells.[2] |
Molecular Weight | 438.58 |
Formula | C15H16BrCl3N4 |
Cas No. | 885104-09-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 90.0 mg/mL (205.2 mM) Methanol: 7.5 mg/mL (17.1 mM) | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
DMSO/Methanol
DMSO
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