Shopping Cart
- Remove All
Your shopping cart is currently empty
MCUF-651
Catalog No. T67734Cas No. 2747162-85-0
MCUF-651 is a guanylyl cyclase A receptor positive allosteric modulators, EC50=0.45 μM.
MCUF-651
Catalog No. T67734Cas No. 2747162-85-0
MCUF-651 is a guanylyl cyclase A receptor positive allosteric modulators, EC50=0.45 μM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $88 | In Stock | |
| 5 mg | $213 | In Stock | |
| 10 mg | $328 | In Stock | |
| 25 mg | $569 | In Stock | |
| 50 mg | $892 | In Stock | |
| 100 mg | $1,360 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $438 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "MCUF-651"
Methylene Blue trihydrate
Methylthionine chloride, Methylene Blue, Basic blue 9
T00067220-79-3
Methylene Blue trihydrate (Basic blue 9) is a compound consisting of dark green crystals or crystalline powder, having a bronze-like luster. Solutions in water or alcohol have a deep blue color. Methylene Blue trihydrate is used as a bacteriologic stain and as an indicator. It inhibits soluble guanylyl cyclase and has been used to treat cyanide poisoning and to lower levels of methemoglobin. It also inhibits tau filament formation (IC50: 1.9μM).
- $42
Size
QTY
Methylene Blue
Cited
Tetramethylthionine chloride, methylthioninium chloride, CI-52015, Basic Blue 9
T688861-73-4
Methylene Blue (Tetramethylthionine chloride) (IC50 of 1.9 μM) inhibits tau filament formation. And it inhibits soluble guanylyl cyclase. It is also used as a dye in chromoendoscopy.
- $30
Size
QTY
CitedNitroprusside disodium dihydrate
Sodium Nitroprusside Dihydrate, Sodium Nitroferricyanide(III) Dihydrate
T699113755-38-9
Nitroprusside disodium dihydrate (Sodium Nitroprusside Dihydrate) is a potent vasodilator working through releasing NO spontaneously in blood.
- $45
Size
QTY
Riociguat
Cited
BAY 632521
T6968625115-55-1
Riociguat (BAY 632521) is a stimulator of guanylate cyclase which causes relaxation of vascular smooth muscle and is used to treat severe pulmonary arterial hypertension.
- $36
Size
QTY
CitedCinaciguat Cited
BAY 58-2667
T1984329773-35-5
Cinaciguat (BAY 58-2667) (BAY 58-2667) is the first of a new class of soluble guanylate cyclase (sGC) activators in Clinicalal development for acute decompensated heart failure.
- $40
Size
QTY
CitedNelociguat
BAY60-4552
T7201625115-52-8
Nelociguat (BAY60-4552)(BAY60-4552) is a soluble guanylate cyclase stimulator (sGC stimulator). Soluble guanylate cyclase (sGC) is a key enzyme in the nitric oxide (NO) signalling pathway.
- $31
Size
QTY
LY83583
6-anilinoquinoline-5,8-dione, 6-Anilino-5,8-quinolinedione
T2157691300-60-6In house
LY83583 is a soluble guanylate cyclase competitive inhibitor with IC50 of 2 µM.
- $55
Size
QTY
Sinitrodil
ITF-296, ITF296, ITF 296
T34648143248-63-9In house
Sinitrodil (ITF-296) is a guanylate cyclase stimulant that may be used in the treatment of myocardial ischemia and angina pectoris.
- $142
Size
QTY
Vericiguat
BAY1021189
T172261350653-20-1
Vericiguat (BAY1021189) is a potent and orally available guanylate cyclase stimulator.
- $40
Size
QTY
Lificiguat Cited
YC-1
T4381170632-47-0
Lificiguat (YC-1) is an nitric oxide (NO)-independent activator of soluble guanylyl cyclase(sGC) and an inhibitor of Hypoxia-inducible factor-1alpha (HIF-1alpha).
- $43
Size
QTY
CitedODQ
T1977741443-28-1
ODQ is an effective and selective soluble guanylyl cyclase (sGC) inhibitor.
- $42
Size
QTY
BAY 41-8543
T21712256498-66-5
BAY 41-8543 is a nitric oxide (NO)-independent stimulator of soluble guanylyl cyclase (sGC).
- $32
Size
QTY
Select Batch
Purity:99.57%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | MCUF-651 is a guanylyl cyclase A receptor positive allosteric modulators, EC50=0.45 μM. |
| Molecular Weight | 368.44 |
| Formula | C17H22F2N4OS |
| Cas No. | 2747162-85-0 |
Storage & Solubility Information
| Storage | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 55 mg/mL (149.27 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy MCUF-651 | purchase MCUF-651 | MCUF-651 cost | order MCUF-651 | MCUF-651 chemical structure | MCUF-651 formula | MCUF-651 molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.