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Meclinertant
🥰Excellent
Catalog No. T16034Cas No. 146362-70-1
Alias SR 48692
Meclinertant (SR 48692) is a neurotensin receptor-1 (NT1) antagonist that blocks neurotensin-induced excitation and can be used to study neurological disorders.
Meclinertant
🥰Excellent
Purity: 99.35%
Catalog No. T16034Alias SR 48692Cas No. 146362-70-1
Meclinertant (SR 48692) is a neurotensin receptor-1 (NT1) antagonist that blocks neurotensin-induced excitation and can be used to study neurological disorders.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $78 | In Stock | |
| 2 mg | $136 | In Stock | |
| 5 mg | $297 | In Stock | |
| 10 mg | $575 | In Stock | |
| 25 mg | $923 | In Stock | |
| 50 mg | $1,260 | In Stock | |
| 100 mg | $1,690 | In Stock |
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Purity:99.35%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Meclinertant (SR 48692) is a neurotensin receptor-1 (NT1) antagonist that blocks neurotensin-induced excitation and can be used to study neurological disorders. |
| In vitro | The neurotensin-induced excitation was selectively blocked by the non-peptide neurotensin receptor antagonist SR 48692, primarily observed in the ventral part of the nucleus[1]. |
| In vivo | SR 48692 can antagonize the induced turning behavior in mice and rats, and reverse the inhibition of amphetamine-induced hyperactivity in rats by neurotensin[2]. |
| Alias | SR 48692 |
| Molecular Weight | 587.07 |
| Formula | C32H31ClN4O5 |
| Cas No. | 146362-70-1 |
| Smiles | O=C(O)C1(NC(=O)C2=NN(C=3C=CN=C4C=C(Cl)C=CC43)C(=C2)C=5C(OC)=CC=CC5OC)C6CC7CC(C6)CC1C7 |
| Relative Density. | 1.50 g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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