Shopping Cart
- Remove All
- Your shopping cart is currently empty
MK-0773 (PF-05314882) is a selective androgen receptor modulator that binds to AR (IC50: 6.6 nM) for the study of diseases caused by endocrine abnormalities.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $78 | In Stock | |
5 mg | $188 | In Stock | |
10 mg | $289 | In Stock | |
1 mL x 10 mM (in DMSO) | $196 | In Stock |
Description | MK-0773 (PF-05314882) is a selective androgen receptor modulator that binds to AR (IC50: 6.6 nM) for the study of diseases caused by endocrine abnormalities. |
Targets&IC50 | Androgen receptor:6.6 nM |
In vitro | The affinity of MK-0773 for AR across species can be evaluated using COS cells transfected with AR, with respective IC50 values as follows: rat, 0.50 nM; dog, 0.55 nM; rhesus, 0.45 nM; human, 0.65 nM[1]. |
In vivo | Treatment of OVX rats with MK-0773 (5 mg/kg, 25 mg/kg), 2-FPA, TFM-4AS-1, and DHT for 24 days resulted in a decrease in total cholesterol and high-density lipoprotein by 25-37%[1]. |
Alias | PF-05314882 |
Molecular Weight | 479.59 |
Formula | C27H34FN5O2 |
Cas No. | 606101-58-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | DMSO: 20 mg/mL (41.70 mM), Sonication is recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
|
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.