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ML402

🥰Excellent
Catalog No. T16109Cas No. 298684-44-3
Alias ZINC3671497, N-[2-(4-chloro-2-methylphenoxy)ethyl]thiophene-2-carboxamide

ML402 (ZINC3671497) is an activator of TREK-1 and TREK-2 with EC50s of 13.7 μM and 5.9 μM.

ML402

ML402

🥰Excellent
Purity: 98.93%
Catalog No. T16109Alias ZINC3671497, N-[2-(4-chloro-2-methylphenoxy)ethyl]thiophene-2-carboxamideCas No. 298684-44-3
ML402 (ZINC3671497) is an activator of TREK-1 and TREK-2 with EC50s of 13.7 μM and 5.9 μM.
Pack SizePriceAvailabilityQuantity
1 mg$31In Stock
2 mg$44In Stock
5 mg$72In Stock
10 mg$122In Stock
25 mg$247In Stock
50 mg$397In Stock
100 mg$589In Stock
500 mg$1,280In Stock
1 mL x 10 mM (in DMSO)$79In Stock
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Purity:98.93%
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Product Introduction

Bioactivity
Description
ML402 (ZINC3671497) is an activator of TREK-1 and TREK-2 with EC50s of 13.7 μM and 5.9 μM.
In vitro
ML402 targets TRAAK with EC50 of 13.6 μM[1].
AliasZINC3671497, N-[2-(4-chloro-2-methylphenoxy)ethyl]thiophene-2-carboxamide
Chemical Properties
Molecular Weight295.78
FormulaC14H14ClNO2S
Cas No.298684-44-3
SmilesCc1cc(Cl)ccc1OCCNC(=O)c1cccs1
Relative Density.1.272 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 95 mg/mL (321.18 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.3809 mL16.9045 mL33.8089 mL169.0446 mL
5 mM0.6762 mL3.3809 mL6.7618 mL33.8089 mL
10 mM0.3381 mL1.6904 mL3.3809 mL16.9045 mL
20 mM0.1690 mL0.8452 mL1.6904 mL8.4522 mL
50 mM0.0676 mL0.3381 mL0.6762 mL3.3809 mL
100 mM0.0338 mL0.1690 mL0.3381 mL1.6904 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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