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Moslosooflavone
🥰Excellent
Catalog No. T5773Cas No. 3570-62-5
Alias 5-hydroxy-7,8-dimethoxyflavone
Moslosooflavone (5-hydroxy-7,8-dimethoxyflavone) has anti-hypoxia activity, it can significantly prolong the survival time of hypoxic mice. 5-hydroxy-7,8-dimethoxyflavone significantly inhibits the transcriptional activity of NF-kappaB in LPS/IFN-gamma stimulated RAW 264.7 macrophages.
Moslosooflavone
🥰Excellent
Purity: 99.78%
Catalog No. T5773Alias 5-hydroxy-7,8-dimethoxyflavoneCas No. 3570-62-5
Moslosooflavone (5-hydroxy-7,8-dimethoxyflavone) has anti-hypoxia activity, it can significantly prolong the survival time of hypoxic mice. 5-hydroxy-7,8-dimethoxyflavone significantly inhibits the transcriptional activity of NF-kappaB in LPS/IFN-gamma stimulated RAW 264.7 macrophages.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $84 | In Stock | |
| 5 mg | $196 | In Stock | |
| 10 mg | $295 | In Stock | |
| 25 mg | $497 | In Stock | |
| 50 mg | $723 | In Stock | |
| 100 mg | $987 | In Stock | |
| 500 mg | $1,980 | In Stock |
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Purity:99.78%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Moslosooflavone (5-hydroxy-7,8-dimethoxyflavone) has anti-hypoxia activity, it can significantly prolong the survival time of hypoxic mice. 5-hydroxy-7,8-dimethoxyflavone significantly inhibits the transcriptional activity of NF-kappaB in LPS/IFN-gamma stimulated RAW 264.7 macrophages. |
| In vitro | 5-hydroxy-7,8-dimethoxyflavone significantly decreased TNF-alpha, IL-6, macrophage inflammatory protein-2 (MIP-2), and nitric oxide (NO) secretions from LPS/IFN-gamma stimulated RAW 264.7 cells[1]. |
| In vivo | 5-hydroxy-7,8-dimethoxyflavone can significantly prolong the survival time of hypoxic mice[2]. |
| Animal Research | The chemical constituents, isolated and purified by column chromatography from Saussurea invo lucrata, were identified by several spectroscopic methods. The anti-hypoxic activities of these compounds were examined using the normobaric hypoxic model of mice[2]. |
| Alias | 5-hydroxy-7,8-dimethoxyflavone |
| Molecular Weight | 298.29 |
| Formula | C17H14O5 |
| Cas No. | 3570-62-5 |
| Smiles | COc1cc(O)c2c(oc(cc2=O)-c2ccccc2)c1OC |
| Relative Density. | 1.321g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 10 mg/mL (33.52 mM)  | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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