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MRS 1754
🥰Excellent
Catalog No. T16140Cas No. 264622-58-4
MRS 1754 is a selective antagonist radioligand for the A2B adenosine receptor, exhibiting very low affinity for A1 and A3 receptors in both humans and rats.
MRS 1754
🥰Excellent
Purity: 97.48%
Catalog No. T16140Cas No. 264622-58-4
MRS 1754 is a selective antagonist radioligand for the A2B adenosine receptor, exhibiting very low affinity for A1 and A3 receptors in both humans and rats.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $38 | In Stock | |
| 5 mg | $89 | In Stock | |
| 10 mg | $147 | In Stock | |
| 25 mg | $322 | In Stock | |
| 50 mg | $513 | In Stock | |
| 100 mg | $747 | In Stock |
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Purity:97.48%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | MRS 1754 is a selective antagonist radioligand for the A2B adenosine receptor, exhibiting very low affinity for A1 and A3 receptors in both humans and rats. |
| Targets&IC50 | A2B:1.45±0.21 nM(Ki, human) |
| In vitro | The Ki value for displacement of [3H]MRS 1754 binding to human A2B receptors expressed in HEK-293 cell membranes is 1.45±0.21 nM. The most effective displacer of [3H]MRS 1754 binding is MRS 1754. . |
| Molecular Weight | 486.52 |
| Formula | C26H26N6O4 |
| Cas No. | 264622-58-4 |
| Smiles | CCCn1c2[nH]c(nc2c(=O)n(CCC)c1=O)-c1ccc(OCC(=O)Nc2ccc(cc2)C#N)cc1 |
| Relative Density. | 1.38g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO: ＜1 mg/mL (insoluble or slightly soluble), Sonication is recommended.  |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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