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N-Deshydroxyethyl Dasatinib

Catalog No. T18750Cas No. 910297-51-7
Alias N-Deshydroxyethyl BMS-354825

N-Deshydroxyethyl Dasatinib (N-Deshydroxyethyl BMS-354825) is a metabolite of Dasatinib, a dasatinib-based molecule that degrades ABL by binding to the IAP ligand via a linker to form SNIPER. N-Deshydroxyethyl Dasatinib is used in the study of cancer and immune diseases.

N-Deshydroxyethyl Dasatinib

N-Deshydroxyethyl Dasatinib

Purity: 95.96%
Catalog No. T18750Alias N-Deshydroxyethyl BMS-354825Cas No. 910297-51-7
N-Deshydroxyethyl Dasatinib (N-Deshydroxyethyl BMS-354825) is a metabolite of Dasatinib, a dasatinib-based molecule that degrades ABL by binding to the IAP ligand via a linker to form SNIPER. N-Deshydroxyethyl Dasatinib is used in the study of cancer and immune diseases.
Pack SizePriceAvailabilityQuantity
1 mg$84In Stock
5 mg$198In Stock
10 mg$313In Stock
25 mg$543In Stock
50 mg$789In Stock
100 mg$1,080In Stock
500 mg$2,180In Stock
1 mL x 10 mM (in DMSO)$226In Stock
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Purity:95.96%
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Product Introduction

Bioactivity
Description
N-Deshydroxyethyl Dasatinib (N-Deshydroxyethyl BMS-354825) is a metabolite of Dasatinib, a dasatinib-based molecule that degrades ABL by binding to the IAP ligand via a linker to form SNIPER. N-Deshydroxyethyl Dasatinib is used in the study of cancer and immune diseases.
AliasN-Deshydroxyethyl BMS-354825
Chemical Properties
Molecular Weight443.95
FormulaC20H22ClN7OS
Cas No.910297-51-7
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 49.5 mg/mL (111.5 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2525 mL11.2625 mL22.5251 mL112.6253 mL
5 mM0.4505 mL2.2525 mL4.5050 mL22.5251 mL
10 mM0.2253 mL1.1263 mL2.2525 mL11.2625 mL
20 mM0.1126 mL0.5631 mL1.1263 mL5.6313 mL
50 mM0.0451 mL0.2253 mL0.4505 mL2.2525 mL
100 mM0.0225 mL0.1126 mL0.2253 mL1.1263 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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