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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $148 | In Stock | |
5 mg | $336 | In Stock | |
10 mg | $493 | In Stock | |
25 mg | $790 | In Stock | |
50 mg | $1,120 | In Stock | |
100 mg | $1,490 | In Stock |
Description | N-piperidine Ibrutinib is a potent BTK inhibitor with IC50s of 51.0 for WT BTK and 30.7 nM for C481S BTK respectively. N-piperidine Ibrutinib can be used as a BTK ligand in the synthesis of a series of PROTACs, such as SJF620. SJF620 is a potent PROTAC BTK degrader with a DC50 of 7.9 nM. |
In vitro | N-piperidine Ibrutinib can be used as a BTK ligand in the synthesis of a series of PROTACs. SJF638, SJF678, and SJF608 are potent PROTAC BTK degraders with DC50s of 374, 162, and 8.3 nM, respectively[2]. |
Molecular Weight | 386.45 |
Formula | C22H22N6O |
Cas No. | 330785-90-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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