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NaV1.2/1.6 channel blocker-1
🥰Excellent
Catalog No. T72170Cas No. 1199944-04-1
NaV1.2/1.6 channel blocker-1 is a potent inhibitor of NaV1.2 and NaV1.6 channels, exhibiting inhibitory effects on rNaV1.6 and hNaV1.2. This compound can be utilized in the study of generalized epilepsy and movement disorders.
NaV1.2/1.6 channel blocker-1
🥰Excellent
Purity: 99.54%
Catalog No. T72170Cas No. 1199944-04-1
NaV1.2/1.6 channel blocker-1 is a potent inhibitor of NaV1.2 and NaV1.6 channels, exhibiting inhibitory effects on rNaV1.6 and hNaV1.2. This compound can be utilized in the study of generalized epilepsy and movement disorders.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $34 | In Stock | |
| 5 mg | $78 | In Stock | |
| 10 mg | $119 | In Stock | |
| 25 mg | $239 | In Stock | |
| 50 mg | $355 | In Stock | |
| 100 mg | $527 | In Stock |
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Purity:99.54%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | NaV1.2/1.6 channel blocker-1 is a potent inhibitor of NaV1.2 and NaV1.6 channels, exhibiting inhibitory effects on rNaV1.6 and hNaV1.2. This compound can be utilized in the study of generalized epilepsy and movement disorders. |
| Targets&IC50 | Nav1.2 (human):24.4 μM, rNaV1.6:9.8 μM |
| In vitro | NaV1.2/1.6 channel blocker(Compound 13)inhibits 48.5% and 34.0% of NaV1.6 and NaV1.2 sodium currents, respectively, in HEK 293 cells stably expressing rat NaV1.6 and human NaV1.2 isoforms at concentrations ranging from 1 to 100 μM [1]. |
| Molecular Weight | 258.34 |
| Formula | C14H14N2OS |
| Cas No. | 1199944-04-1 |
| Smiles | S=C1OC=2C=CC=CC2C3=NC(=C(N13)CCC)C |
Storage & Solubility Information
| Storage | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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