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PF-06651481-00

Catalog No. T28374Cas No. 1391063-17-4
Alias PF0665148100, PF 06651481 00, Bosutinib Isomer I

PF-06651481-00 (Bosutinib Isomer I) is a Bosutinib analog and a Bcr-Abl inhibitor.

PF-06651481-00

PF-06651481-00

Purity: 95%
Catalog No. T28374Alias PF0665148100, PF 06651481 00, Bosutinib Isomer ICas No. 1391063-17-4
PF-06651481-00 (Bosutinib Isomer I) is a Bosutinib analog and a Bcr-Abl inhibitor.
Pack SizePriceAvailabilityQuantity
1 mg$35In Stock
5 mg$81In Stock
10 mg$129In Stock
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Purity:95%
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Product Introduction

Bioactivity
Description
PF-06651481-00 (Bosutinib Isomer I) is a Bosutinib analog and a Bcr-Abl inhibitor.
AliasPF0665148100, PF 06651481 00, Bosutinib Isomer I
Chemical Properties
Molecular Weight530.45
FormulaC26H29Cl2N5O3
Cas No.1391063-17-4
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 9.0 mg/mL (17.0 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.8852 mL9.4260 mL18.8519 mL94.2596 mL
5 mM0.3770 mL1.8852 mL3.7704 mL18.8519 mL
10 mM0.1885 mL0.9426 mL1.8852 mL9.4260 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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