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PIK-294

PIK-294
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Purity:100%
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PIK-294

Catalog No. T2297Cas No. 900185-02-6
PIK-294 is a excellently specific p110δ inhibitor(IC50=10 nM).
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
1 mg$30In Stock
2 mg$40In Stock
5 mg$64In Stock
10 mg$113In Stock
25 mg$180In Stock
50 mg$288In Stock
100 mg$450In Stock
1 mL x 10 mM (in DMSO)$68In Stock
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Product Introduction

Bioactivity
Description
PIK-294 is a excellently specific p110δ inhibitor(IC50=10 nM).
Targets&IC50
p110δ:10 nM
In vivo
PIK-294 exhibits inhibitory effects on various PI3K isoforms, including p110β, p110δ, and p110γ; however, it demonstrates low selectivity towards p110α.
AliasPIK294
Chemical Properties
Molecular Weight489.53
FormulaC28H23N7O2
Cas No.900185-02-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 91 mg/mL (185.9 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.0428 mL10.2139 mL20.4278 mL102.1388 mL
5 mM0.4086 mL2.0428 mL4.0856 mL20.4278 mL
10 mM0.2043 mL1.0214 mL2.0428 mL10.2139 mL
20 mM0.1021 mL0.5107 mL1.0214 mL5.1069 mL
50 mM0.0409 mL0.2043 mL0.4086 mL2.0428 mL
100 mM0.0204 mL0.1021 mL0.2043 mL1.0214 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
1 Enter information below:
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2 Enter the in vivo formulation:
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