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RMC-4630

🥰Excellent
Catalog No. T39658Cas No. 2172652-48-9
Alias SHP2-IN-7, RMC-4630

RMC-4630 (SHP2-IN-7) is an inhibitor of SHP2.

RMC-4630

RMC-4630

🥰Excellent
Purity: 99.07%
Catalog No. T39658Alias SHP2-IN-7, RMC-4630Cas No. 2172652-48-9
RMC-4630 (SHP2-IN-7) is an inhibitor of SHP2.
Pack SizePriceAvailabilityQuantity
1 mg$148In Stock
5 mg$372In Stock
10 mg$556In Stock
25 mg$896In Stock
50 mg$1,220In Stock
100 mg$1,650In Stock
1 mL x 10 mM (in DMSO)$397In Stock
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Purity:99.07%
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Product Introduction

Bioactivity
Description
RMC-4630 (SHP2-IN-7) is an inhibitor of SHP2.
AliasSHP2-IN-7, RMC-4630
Chemical Properties
Molecular Weight450.99
FormulaC20H27ClN6O2S
Cas No.2172652-48-9
SmilesC[C@@H]1OCC2(CCN(CC2)c2nc(C)c(Sc3ccnc(N)c3Cl)nc2CO)[C@@H]1N
Relative Density.1.44 g/cm3 (Predicted)
Storage & Solubility Information
Storagekeep away from direct sunlight,keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 45 mg/mL (99.78 mM), Sonication and heating to 60℃ are recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2173 mL11.0867 mL22.1734 mL110.8672 mL
5 mM0.4435 mL2.2173 mL4.4347 mL22.1734 mL
10 mM0.2217 mL1.1087 mL2.2173 mL11.0867 mL
20 mM0.1109 mL0.5543 mL1.1087 mL5.5434 mL
50 mM0.0443 mL0.2217 mL0.4435 mL2.2173 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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