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Ro 20-1724
🥰Excellent
Catalog No. T19706Cas No. 29925-17-5
Alias Ro20-1724, Ro-20-1724, 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone
Ro 20-1724 (4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone) is a widely used inhibitor of cyclic nucleotide phosphodiesterase with IC50 of 2.0 μM and Ki of 3.1 μM.
Ro 20-1724
🥰Excellent
Purity: 99.14%
Catalog No. T19706Alias Ro20-1724, Ro-20-1724, 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinoneCas No. 29925-17-5
Ro 20-1724 (4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone) is a widely used inhibitor of cyclic nucleotide phosphodiesterase with IC50 of 2.0 μM and Ki of 3.1 μM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $40 | In Stock | |
| 10 mg | $64 | In Stock | |
| 25 mg | $128 | In Stock |
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Purity:99.14%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Ro 20-1724 (4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone) is a widely used inhibitor of cyclic nucleotide phosphodiesterase with IC50 of 2.0 μM and Ki of 3.1 μM. |
| Targets&IC50 | PDE4:2.0 μM, PDE4:3.1 μM(Ki) |
| In vivo | RO-20-1724 was found to not only improve learning and memory in MWM and PA paradigms but also restore STZ induced elevation in cholinesterase activity. Further, RO-20-1724 significantly reduced malondialdehyde and nitrite levels, and restored the glutathione levels indicating attenuation of oxidative stress[2]. |
| Alias | Ro20-1724, Ro-20-1724, 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone |
| Molecular Weight | 278.35 |
| Formula | C15H22N2O3 |
| Cas No. | 29925-17-5 |
| Smiles | CCCCOC1=C(OC)C=CC(CC2CNC(=O)N2)=C1 |
| Relative Density. | 1.099 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (179.63 mM) Ethanol: 50 mg/mL (179.63 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO/Ethanol
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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