Shopping Cart

Remove All

Your shopping cart is currently empty

Ro 20-1724

Select Batch

Purity:99.14%

Resource Download

COA HNMR HPLC

Ro 20-1724

Catalog No. T19706Cas No. 29925-17-5

Ro 20-1724 (4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone) is a widely used inhibitor of cyclic nucleotide phosphodiesterase with IC50 of 2.0 μM and Ki of 3.1 μM.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
2 mg	$37	In Stock
5 mg	$48	In Stock
10 mg	$75	In Stock
25 mg	$135	In Stock

Bulk & Custom

Add to Cart

Questions

Related Compound Libraries of "Ro 20-1724"

Product Introduction

Bioactivity

Description	Ro 20-1724 (4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone) is a widely used inhibitor of cyclic nucleotide phosphodiesterase with IC50 of 2.0 μM and Ki of 3.1 μM.
In vivo	RO-20-1724 was found to not only improve learning and memory in MWM and PA paradigms but also restore STZ induced elevation in cholinesterase activity. Further, RO-20-1724 significantly reduced malondialdehyde and nitrite levels, and restored the glutathione levels indicating attenuation of oxidative stress[2].
Alias	Ro-20-1724, 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone, Ro20-1724

Chemical Properties

Molecular Weight	278.35
Formula	C15H22N2O3
Cas No.	29925-17-5

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/Ml(179.63 mM)

Ethanol: 50 mg/Ml(179.63 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.5926 mL	17.9630 mL	35.9260 mL	179.6300 mL
5 mM	0.7185 mL	3.5926 mL	7.1852 mL	35.9260 mL
10 mM	0.3593 mL	1.7963 mL	3.5926 mL	17.9630 mL
20 mM	0.1796 mL	0.8981 mL	1.7963 mL	8.9815 mL
50 mM	0.0719 mL	0.3593 mL	0.7185 mL	3.5926 mL
100 mM	0.0359 mL	0.1796 mL	0.3593 mL	1.7963 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc