Home Tools
Log in
Cart

Search Result

Search Results for " cognitive "

Targets

176

Compounds

32

Natural Products

17

Recombinant Proteins

3

Libraries

Cat No. Product Name Synonyms Targets
T4262 BisfluoroModafinil Dopamine Receptor
CRL-40940 is a selective dopaminergic reuptake inhibitor
T0940 Acesulfame Potassium Others
Acesulfame potassium is a non-nutritive sweetener.
T7829 FK962 Somatostatin
FK962 is an somatostatin release enhancer , exerts cognitive-enhancing actions.
T11689 ITI-214 ITI214 PDE
ITI-214 is a picomolar PDE1 inhibitor with excellent selectivity against other PDE family members and against a panel of enzymes, receptors, transporters, and ion channels, exhibits potent PDE1 inhibitory activity (Ki = ...
T0322 Fipexide Dopamine Receptor , AChR
Fipexide (Attentil, Vigilor), a psychoactive drug of the piperazine chemical class, was developed in Italy in 1983. It was served as a nootropic drug in France and Italy, mainly for the therapy of senile dementia, but is...
T9070 ASP2905 ASP-2905 Potassium Channel
ASP-2905 is a potent and selective inhibitor of potassium channel Kv12.2 encoded by the Kcnh3/BEC1 gene. It can cross the blood-brain barrier and has antipsychotic activities
T8737 GR 125743 5-HT Receptor
GR 125743 is a novel antagonist of 5-HT1B/1D receptor.
T8390 Cefazolin Others , Antibacterial , Antibiotic
Cefazolin is a semi-synthetic cephalosporin that has a broad spectrum of antibacterial activity and inhibits the synthesis of bacterial cell walls.
T4576 Perospirone Lullan Dopamine Receptor , 5-HT Receptor
Perospirone (Lullan) is an antagonist of serotonin 5HT2A receptors and dopamine D2 receptors. It also displays affinity towards 5HT1A receptors as a partial agonist.
T12165 NAChR agonist 1 DUN71755 AChR
nAChR agonist 1 (DUN71755) is a brain-permeable and orally efficacious positive allosteric α7 nicotinic acetylcholine receptor (α7 nAChR)modulator.
T22012 7BIO FLT , DYRK , Aurora Kinase
7-bromoindirubin-3'-oxime (7BIO) is a caspase independent nonapoptotic cell death inducer. 7BIO is an inhibitor of FLT3, DYRK1A, DYRK2, Aurora B and Aurora C kinases.
T7530 PD146176 NSC168807 Ferroptosis , Lipoxygenase , Autophagy
PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM. PD146176 reverses cognitive impairment, brain amyloidosis, and tau pathology...
T8720 PRX-07034 hydrochloride PRX-07034 5-HT Receptor
PRX-07034 hydrochloride is a selective antagonist of 5-HT6 receptor. It has cognition and memory-enhancing properties and potently decreases food intake and body weight in rodents. PRX-07034 hydrochloride is both a poten...
T28368 PF-04859989 HCl PF 04859989,PF04859989,PF-04859989HCl,PF-04859989 Others
PF-04859989 HCl is a brain-penetrable irreversible inhibitor of kynurenine amino transferase II (KAT II), the enzyme responsible for most of the brain synthesis of kynurenic acid. PF-04859989 HCl has been implicated in s...
T2150 Guanfacine hydrochloride Tenex,Intuniv,Guanfacine Adrenergic Receptor
Guanfacine hydrochloride (Intuniv) is a centrally acting antihypertensive agent with specificity towards ADRENERGIC ALPHA-2 RECEPTORS.
T22016 A-582941 dihydrochloride A 582941 5-HT Receptor , AChR
A-582941 dihydrochloride (A 582941) is a Selective agonist of α7 nAChR partial
T7823 IDRA-21 GluR
IDRA-21 is a positive AMPA receptor modulator.
T23008L MMPIP hydrochloride MMPIP hydrochloride (479077-02-6 Free base) GluR
MMPIP hydrochloride is a selective antagonist of allosteric mGluR7. MMPIP hydrochloride can be used in research on the roles of mGluR7 on central nervous system functions.
T1780 Parecoxib SC 69124,Vorth-P,Valus-P COX
Parecoxib (SC 69124) is an effective and selective COX-2 inhibitor.
T6493 Escitalopram Oxalate Cipralex,(S)-(+)Citalopram oxalate Others , 5-HT Receptor , Serotonin Transporter
Escitalopram Oxalate ((S)-(+)Citalopram oxalate) is a selective serotonin (5-HT) reuptake inhibitor (SSRI) with Ki of 0.89 nM.
T7165 Basmisanil RG1662,RO5186582 GABA Receptor
Basmisanil (RG1662) is a negative allosteric modulator/inverse agonist of GABAAα5 receptors.Formulations containing basmisanil are in clinical trials for the treatment of cognitive impairments associated with Down syndro...
T8136 Perospirone hydrochloride Perospirone HCl,SM-9018 hydrochloride Dopamine Receptor , 5-HT Receptor
Perospirone hydrochloride (Perospirone HCl) is an atypical antipsychotic agent for the treatment of schizophrenia. It also displays affinity towards 5HT1A receptors as a partial agonist.
T0953 Cefazolin sodium Ancef,Cefazolin sodium salt,Sodium cephazolin,cephazolin sodium,cefazoline sodium,Sodium cefazolin Others , Antibacterial , Antibiotic
Cefazolin sodium (cephazolin sodium) salt binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Cefazolin sodium salt is the sodium salt of cefazolin, a beta...
T1406 Amantadine hydrochloride 1-adamantanamine HCl,1-Adamantanamine hydrochloride,Symmetrel,CI-719,Amantadine HCl,1-Adamantylamine hydrochloride Dopamine Receptor , Influenza Virus
Amantadine hydrochloride (CI-719) is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A and Parkinson disease.
T19706 Ro 20-1724 Ro-20-1724,4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone,Ro20-1724 PDE
Ro 20-1724 (4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone) is a widely used inhibitor of cyclic nucleotide phosphodiesterase with IC50 of 2.0 μM and Ki of 3.1 μM.
T16881 SIB-1553A hydrochloride Others
SIB-1553A is an orally bioavailable nicotinic acetylcholine receptors agonist. SIB-1553A is also a selective neuronal nAChR ligand. SIB-1553A is a cognitive enhancer and has therapeutic potential for the symptomatic trea...
T0183 Pramiracetam CI-879 Others
Pramiracetam (CI-879), derived from piracetam, is a more effective nootropic drug . According to reports, Pramiracetam improved cognitive defects related with traumatic brain wounds. Pramiracetam was also potent in the t...
T30549 BMY-21502 Bms181168,Bms 181168,Bms-181168
BMY-21502 is an identified potential cognitive enhancer, an nootropic agent. In studies it has shown to protect rodents from ECS-induced amnesia in a step-down passive avoidance task.
T27462 GSK-239512 GSK239512,GSK 239512 Histamine Receptor
GSK-239512 is an antagonist of H3 receptor and can be used in studies about the treatment of cognitive dysfunction in neurodegenerative disorders.
T13151L THK5351 Others
THK5351 is a tracer involved in PET imaging for electron emission tomography imaging of Alzheimer's disease and cognitive impairment.
T10499 H3 receptor-MO-1 Histamine Receptor
H3 receptor-MO-1 is a potent modulator of the histamine H3 receptor (H3 receptor) and can be used to study neurodegeneration and cognitive disorders.
T8585 TA-03 7-Methoxytacrine,7-Meota AChE
TA-03 (7-Meota) is a potent inhibitor of AChE in treatment of cognitive manifestation of AD.
T1128 Oxiracetam ISF2522 GABA Receptor
Oxiracetam (ISF2522), a cyclic derivative of gamma-aminobutyric acid (GABA), is utilized for the treatment of cognitive impairments.
T16816 S 18986 GluR
S 18986 is a selective, orally active, brain penetrant positive allosteric modulator of AMPA-type receptors, showcasing cognitive-enhancing properties in rodents. It induces the release of noradrenaline and acetylcholine...
T7580 CX546 Autophagy , iGluR
CX546 is an AMPA receptor modulator. CX546 enhances cognitive function in rats. It has also been proposed as a treatment for schizophrenia.
T0426 Piracetam UCB-6215 GluR , iGluR
Piracetam (UCB-6215), a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), is used in therapy of the extensive cognitive disorders.
T1884 CX516 Ampakine CX516,BDP 12,Ampalex GluR , iGluR
CX516 (Ampalex), an ampakine and nootropic, acts as an AMPA receptor positive allosteric modulator as a therapy for Alzheimer's disease, schizophrenia and mild cognitive impairment (MCI).
T22378 Nilotinib hydrochloride AMN-107 HCl Bcr-Abl , Autophagy
Nilotinib hydrochloride(AMN-107 HCl) is an orally available Bcr-Abl tyrosine kinase inhibitor with antitumor activity for modulation of neuroinflammation and cognitive deficits, and may be used in studies of chronic myel...
T27636 Ispronicline AZD-3480,RJR-1734,AZD 3480,TC 1734,AZD3480,TC-01734,TC-1734-112 AChR
Ispronicline (TC-1734) An orally active, selective, and potent α4β2 nAChR partial agonist with antidepressant, neuroprotective, and long-lasting cognitive effects.Ispronicline has a high affinity for the α4β2 nAChR with ...
T7193 Encenicline EVP-6124 AChR
Encenicline (EVP-6124) is a selective α7 nicotinic acetylcholine receptor (nAChRs) agonist in development for treating cognitive impairment in schizophrenia and Alzheimer's disease.
T62839 Dalzanemdor SAGE-718 NMDAR , iGluR
Dalzanemdor (SAGE-718) is an NMDA receptor-positive modulator of metabolism that can be used to study Huntington's chorea, Alzheimer's disease, and cognitive dysfunction.
T7108 Omberacetam SGS-111,Noopept,GVS-111 Others , iGluR
Omberacetam (Noopept) is a synthetic dipeptide that has been shown to produce positive nootropic and cognitive effects in animal models by a mechanism similar to other related racetam compounds.
T14507 Bay 60-7550 BAY 607550 PDE
Bay 60-7550 is a selective and potent PDE2 inhibitor (Ki: 3.8 nM) that exerts positive inotropic effects on rat heart by increasing PKA-mediated phosphorylation and can be used to ameliorate cognitive impairments and mem...
T61278 Aminopeptidase-IN-1 Aminopeptidase
Aminopeptidase-IN-1 is a potent inhibitor of insulin-regulated aminopeptidase (IRAP) (Ki: 7.7 μM).Aminopeptidase-IN-1 can be used in studies of cognitive and memory disorders.
T8451 Tropanserin MDL 72422 5-HT Receptor
Tropanserin (MDL 72422) is a 5-hydroxytryptamine receptor antagonist that inhibits 5-HT3 receptor activity.Tropanserin has anxiolytic activity and is used to treat depression and cognitive disorders.
T21470L Davunetide acetate Davunetide acetate(211439-12-2 Free base) Beta Amyloid , Microtubule Associated
Davunetide acetate is derived from activity-dependent neuroprotective protein existing in the mammalian CNS. Davunetide acetate is a microtubule-stabilizing peptide and inhibits Aβ aggregation and Aβ-induced neurotoxicit...
T23145 PHA 543613 Others , AChR
PHA 543613 is a specific agonist of α7 nAChR (Ki = 8.8 nM) and can be used in studies about the cognitive deficits of Alzheimer's disease and schizophrenia.
T0869 Atomoxetine hydrochloride Tomoxetine hydrochloride,(R)-Tomoxetine hydrochloride,LY 139603,Atomoxetine HCl,LY 139603 HCl Dopamine Receptor , 5-HT Receptor , Norepinephrine
Atomoxetine hydrochloride (LY 139603) is the hydrochloride salt of atomoxetine, a phenoxy-3-propylamine derivative and selective non-stimulant, norepinephrine reuptake inhibitor with cognitive-enhancing activity. Althou...
T30579 BRD4097 HDAC
BRD4097, a negative control in the HDAC1/2/3/8 assay, is a selective histone deacetylase (HDAC3) inhibitor that can be used to protect b-cells and improve insulin resistance, help promote cognitive function and enhance l...
T77678 TZ3O AChR
TZ3O is an anticholinergic compound with neuroprotective activity.TZ3O ameliorates memory impairment and cognitive decay in Scopolamine-induced Alzheimer's type model in rats, and can be used in the study of Alzheimer's ...

Compounds

BisfluoroModafinil
T4262
Synonym:
Target: Dopamine Receptor
Acesulfame Potassium
T0940
Synonym:
Target: Others
FK962
T7829
Synonym:
Target: Somatostatin
ITI-214
T11689
Synonym: ITI214
Target: PDE
Fipexide
T0322
Synonym:
Target: Dopamine Receptor, AChR
ASP2905
T9070
Synonym: ASP-2905
Target: Potassium Channel
GR 125743
T8737
Synonym:
Target: 5-HT Receptor
Cefazolin
T8390
Synonym:
Target: Others, Antibacterial, Antibiotic
Perospirone
T4576
Synonym: Lullan
Target: Dopamine Receptor, 5-HT Receptor
nAChR agonist 1
T12165
Synonym: DUN71755
Target: AChR
7BIO
T22012
Synonym:
Target: FLT, DYRK, Aurora Kinase
PD146176
T7530
Synonym: NSC168807
Target: Ferroptosis, Lipoxygenase, Autophagy
PRX-07034 hydrochloride
T8720
Synonym: PRX-07034
Target: 5-HT Receptor
PF-04859989 HCl
T28368
Synonym: PF 04859989,PF04859989,PF-04859989HCl,PF-04859989
Target: Others
Guanfacine hydrochloride
T2150
Synonym: Tenex,Intuniv,Guanfacine
Target: Adrenergic Receptor
A-582941 dihydrochloride
T22016
Synonym: A 582941
Target: 5-HT Receptor, AChR
IDRA-21
T7823
Synonym:
Target: GluR
MMPIP hydrochloride
T23008L
Synonym: MMPIP hydrochloride (479077-02-6 Free base)
Target: GluR
Parecoxib
T1780
Synonym: SC 69124,Vorth-P,Valus-P
Target: COX
Escitalopram Oxalate
T6493
Synonym: Cipralex,(S)-(+)Citalopram oxalate
Target: Others, 5-HT Receptor, Serotonin Transporter
Basmisanil
T7165
Synonym: RG1662,RO5186582
Target: GABA Receptor
Perospirone hydrochloride
T8136
Synonym: Perospirone HCl,SM-9018 hydrochloride
Target: Dopamine Receptor, 5-HT Receptor
Cefazolin sodium
T0953
Synonym: Ancef,Cefazolin sodium salt,Sodium cephazolin,cephazolin sodium,cefazoline sodium,Sodium cefazolin
Target: Others, Antibacterial, Antibiotic
Amantadine hydrochloride
T1406
Synonym: 1-adamantanamine HCl,1-Adamantanamine hydrochloride,Symmetrel,CI-719,Amantadine HCl,1-Adamantylamine hydrochloride
Target: Dopamine Receptor, Influenza Virus
Ro 20-1724
T19706
Synonym: Ro-20-1724,4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone,Ro20-1724
Target: PDE
SIB-1553A hydrochloride
T16881
Synonym:
Target: Others
Pramiracetam
T0183
Synonym: CI-879
Target: Others
BMY-21502
T30549
Synonym: Bms181168,Bms 181168,Bms-181168
Target:
GSK-239512
T27462
Synonym: GSK239512,GSK 239512
Target: Histamine Receptor
THK5351
T13151L
Synonym:
Target: Others
H3 receptor-MO-1
T10499
Synonym:
Target: Histamine Receptor
TA-03
T8585
Synonym: 7-Methoxytacrine,7-Meota
Target: AChE
Oxiracetam
T1128
Synonym: ISF2522
Target: GABA Receptor
S 18986
T16816
Synonym:
Target: GluR
CX546
T7580
Synonym:
Target: Autophagy, iGluR
Piracetam
T0426
Synonym: UCB-6215
Target: GluR, iGluR
CX516
T1884
Synonym: Ampakine CX516,BDP 12,Ampalex
Target: GluR, iGluR
Nilotinib hydrochloride
T22378
Synonym: AMN-107 HCl
Target: Bcr-Abl, Autophagy
Ispronicline
T27636
Synonym: AZD-3480,RJR-1734,AZD 3480,TC 1734,AZD3480,TC-01734,TC-1734-112
Target: AChR
Encenicline
T7193
Synonym: EVP-6124
Target: AChR
Dalzanemdor
T62839
Synonym: SAGE-718
Target: NMDAR, iGluR
Omberacetam
T7108
Synonym: SGS-111,Noopept,GVS-111
Target: Others, iGluR
Bay 60-7550
T14507
Synonym: BAY 607550
Target: PDE
Aminopeptidase-IN-1
T61278
Synonym:
Target: Aminopeptidase
Tropanserin
T8451
Synonym: MDL 72422
Target: 5-HT Receptor
Davunetide acetate
T21470L
Synonym: Davunetide acetate(211439-12-2 Free base)
Target: Beta Amyloid, Microtubule Associated
PHA 543613
T23145
Synonym:
Target: Others, AChR
Atomoxetine hydrochloride
T0869
Synonym: Tomoxetine hydrochloride,(R)-Tomoxetine hydrochloride,LY 139603,Atomoxetine HCl,LY 139603 HCl
Target: Dopamine Receptor, 5-HT Receptor, Norepinephrine
BRD4097
T30579
Synonym:
Target: HDAC
TZ3O
T77678
Synonym:
Target: AChR
1 2 3 4
Cat No. Product Name Synonyms Targets
T2S1720 Huperzine B AChE
1. Huperzine-B is a efficient inhibitor of human brain AChE. 2. Huperzine-B can enhance ognitive and protect neuro, may be potentially new drug candidates for Alzheimer's disease therapy.
T3S0195 Nootkatone AMPK
1. Nootkatone can provide effective tick control. 2. (+)-Nootkatone has antiallergic, anti-inflammatory, and antiplatelet activities. 3. Nootkatone can prevent obesity and improve physical performance through AMPK activa...
T4954 SMILAGENIN ACETATE Nsc15488 Others
SMILAGENIN ACETATE is a natural product for research related to life sciences. The catalog number is T4954 and the CAS number is 4947-75-5.
TN2100 Pratensein Others , NF-κB
Pratensein as a novel transcriptional up-regulator of scavenger receptor class B type I in HepG2 cells.
T1589 D-Cycloserine RO-1-9213 Others , Antibacterial , Antibiotic , iGluR
D-Cycloserine (RO-1-9213) is a broad spectrum antibiotic used as a second line agent for treatment of drug resistant tuberculosis, always in combination with other antituberculosis agents.
T0185 Escitalopram Seroplex,S-(+)-Citalopram,(S)-Citalopram Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Adrenergic Receptor , AChR , Norepinephrine , Histamine Receptor
Escitalopram (Seroplex) is a furancarbonitrile that is one of the SEROTONIN UPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patien...
T3026 (-)-Huperzine A HupA,Huperzine A Apoptosis , AChR , AChE , iGluR
(-)-Huperzine A (HupA) , an active Lycopodium alkaloid extracted from the traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the tr...
T6975 Sarcosine Sarcosinic acid,Methylaminoacetic acid,Sarcosin,Methylglycine,N-Methylaminoacetic acid,N-methylglycine Others , GlyT , Endogenous Metabolite
Sarcosine (Methylglycine) is a competitive inhibitor of the type I glycine transporter (GlyT1) and an N-methyl-D-aspartate receptor (NMDAR) co-agonist.
T7060 Amantadine 1-Aminoadamantane,1-Adamantanamine,1-Adamantylamine Others
Amantadine (1-Aminoadamantane) is an antiviral, is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release, and blocks dopamine reuptake.
T5S0833 Astragaloside III Antioxidant
Astragaloside III has cardioprotective effects as well as causing improvement in cognitive function. It can be used in the prevention of cardio-cerebral vascular diseases. It also is antioxidant.
T4S1519 Pseudoginsenoside RT5 Others
1. Pseudoginsenoside RT5 has anti-epilepsy, anti-depressant activity by promoting nerve growth and improve cognitive ability. 2. Pseudoginsenoside RT5 has anti-bacterial, anti-tumor and anti-malaria activities.
T3911 Pulchinenoside A Anemoside A3 Others
Pulchinenoside A (Anemoside A3) is an attractive candidate for further development as a cognitive enhancer capable of alleviating memory dysfunctions associated with aging and neurodegenerative diseases.
T2765 Rosmarinic acid Labiatenic acid,Rosemary acid Apoptosis , IκB/IKK , MAO , Endogenous Metabolite , Transferase , Monoamine Oxidase
Rosmarinic acid (Labiatenic acid) has shown to contain antioxidant, anti-inflammatory and antimicrobial activities. Possesses promising physiological actions related to cognitive performance, Alzheimer′s disease preventi...
TN2703 2,3-Dihydroxy-4-methoxyacetophenone 2',3'-Dihydroxy-4'-methoxyacetophenone Calcium Channel
2,3-Dihydroxy-4-methoxyacetophenone (2',3'-Dihydroxy-4'-methoxyacetophenone) is a natural product,it improves cognitive function and may be helpful for the treatment of Alzheimer's disease.
T3902 Atractylenolide III ICodonolactone,8β-Hydroxyasterolide Apoptosis
Atractylenolide III (ICodonolactone) may have therapeutic potential in treating homocysteine-mediated cognitive impairment and neuronal injury. Atractylenolide III is a potential candidate for the treatment of human lung...
TN1420 Bacopaside I Others
Bacopaside I is a saponin isolated from Bacopa monniera. Bacopaside I is a modulator of Aquaporin-1 channel, has neuroprotective functions, it has anti-Alzheimer's disease, it ameliorates cognitive impairment in APP/PS1 ...
T5702 Tenuifoliside B Dehydrogenase
Tenuifoliside B is a natural product from the roots of Polygala tenuifolia.And is a target lactate dehydrogenase inhibitor. Tenuifoliside B has cognitive improving and cerebral protective effects. it can inhibit potassi...
TN1601 Effusol Caspase
Effusol is a natural product, exhibits potent scavenging activity for DPPH and ABTS radicals(IC50 values of 79 μM and 2.73 μM, respectively). Effusol rescues CA1 LTP attenuated by corticosterone, defending the hippocampa...
T32614 L-Clausenamide (-)-Clausenamide Microtubule Associated
L-Clausenamide is an alkaloid extracted from the leaves of the yellow bark (Clausena lansium (Lour) skeels) and can be used to improve cognitive function. L-Clausenamide inhibits beta-amyloid (Aβ) toxicity and prevents t...
T4439 Sn-Glycero-3-phosphocholine Choline Alfoscerate,Glycerophosphocholine,Glycerophosphorylcholine,Alpha-GPC,Choline glycerophosphate,L-α-GPC Endogenous Metabolite , AChE
sn-Glycero-3-phosphocholine (Choline glycerophosphate) is a natural choline compound found in the brain and in milk. It is also a parasympathomimetic acetylcholine precursor which may have a potential for the treatment o...
T41095 (E)-3-(4-Methoxyphenyl)acrylic acid Glucosidase
(E)-3-(4-Methoxyphenyl)acrylic acid is a small molecule compound isolated from the rhizome of Etlingera pavieana (Pierre ex Gagnep.) R. M. Sm. It is a novel α-glucosidase inhibitor. (E)-3-(4-Methoxyphenyl)acrylic acid ha...
T3767 Polygalacic acid Virgaureagenin G MMP , AChR , AChE
Polygalacic acid (Virgaureagenin G)(PA) significantly improves cholinergic system reactivity, as indicated by decreased acetylcholinesterase (AChE) activity, increases choline acetyltransferase (ChAT) activity, and eleva...
T6S0721 Orientin Lutexin,Luteolin-8-glucoside Others
1. Orientin (Luteolin-8-glucoside) may be regarded as a candidate therapeutic agent for treatment of vascular inflammatory diseases via inhibition of the HMGB1 signaling pathway. 2. Orientin protects vascular barrier int...
T3011 2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid Kynurenine,Dl-Kynurenine,Kynurenin,3-Anthraniloylalanine Others , Endogenous Metabolite
2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid (3-Anthraniloylalanine) is a ketone and an amino acid derivative with diverse biological functions, including vasodilatory, immunoregulatory and neuromodulatory activities. 2-...
T2563 Acetyl-L-carnitine hydrochloride Acetyl L-carnitine hydrochloride,O-Acetylcarnitine,O-acetyl-L-carnitine,O-Acetyl-L-carnitine hydrochloride Others , Endogenous Metabolite
Acetyl-L-carnitine hydrochloride (Acetyl L-carnitine hydrochloride) is a nutritional supplement composed of the hydrochloride salt form of the acetylated form of the endogenously produced L-carnitine, with potential neur...
T4S0969 Obtusifolin Antioxidant , NF-κB
1. Obtusifolin has antioxidant properties and improves chemically induced diabetes and its complications by modulation of oxidative stress. 2. Obtusifolin suppresses phthalate esters-mediated bone resorption, thus may be...
T0591L Galactose alpha-D-Galactose
Galactose prevents cognitive deficits in male Wistar rats.
TN1798 Isorosmanol Beta Amyloid , AChR
Isorosmanol possesses antioxidant, neuroprotective and neurotrophic effects, it might be useful in ageing disorders such as the declining of cognitive functions and hyperpigmentation.
T80631 Esculin sesquihydrate p38 MAPK
Esculin sesquihydrate, a coumarin glucoside with fluorescent properties and a constituent of ash bark, improves cognitive deficits associated with experimental diabetic nephropathy (DN). It also offers anti-oxidative and...
T81072 Suffruticosol A
Suffruticosol A, a neuroprotective compound isolated from the seeds of P. lactiflora [1], mitigates scopolamine-induced neurodegenerative cellular damage and improves hippocampal cholinergic function. Additionally, it pa...
T79963 Feralolide
Feralolide, a dihydroisocoumarin from the methanolic extract of aloe vera resin, functions as a dual inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE), with IC50 values of 55 μg/mL and 52 μg/mL, ...
TJS0123 Guvacine ethyl ester PT00442-2,Arecoline Others
Guvacine ethyl ester (Arecoline) is found in nuts. Arecoline is isolated from betel nuts Arecoline is an alkaloid natural product found in the areca nut, the fruit of the areca palm (Areca catechu). It is an oily liquid ...

Natural Products

Huperzine B
T2S1720
Synonym:
Target: AChE
Nootkatone
T3S0195
Synonym:
Target: AMPK
SMILAGENIN ACETATE
T4954
Synonym: Nsc15488
Target: Others
Pratensein
TN2100
Synonym:
Target: Others, NF-κB
D-Cycloserine
T1589
Synonym: RO-1-9213
Target: Others, Antibacterial, Antibiotic, iGluR
Escitalopram
T0185
Synonym: Seroplex,S-(+)-Citalopram,(S)-Citalopram
Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Adrenergic Receptor, AChR, Norepinephrine, Histamine Receptor
(-)-Huperzine A
T3026
Synonym: HupA,Huperzine A
Target: Apoptosis, AChR, AChE, iGluR
Sarcosine
T6975
Synonym: Sarcosinic acid,Methylaminoacetic acid,Sarcosin,Methylglycine,N-Methylaminoacetic acid,N-methylglycine
Target: Others, GlyT, Endogenous Metabolite
Amantadine
T7060
Synonym: 1-Aminoadamantane,1-Adamantanamine,1-Adamantylamine
Target: Others
Astragaloside III
T5S0833
Synonym:
Target: Antioxidant
Pseudoginsenoside RT5
T4S1519
Synonym:
Target: Others
Pulchinenoside A
T3911
Synonym: Anemoside A3
Target: Others
Rosmarinic acid
T2765
Synonym: Labiatenic acid,Rosemary acid
Target: Apoptosis, IκB/IKK, MAO, Endogenous Metabolite, Transferase, Monoamine Oxidase
2,3-Dihydroxy-4-methoxyacetophenone
TN2703
Synonym: 2',3'-Dihydroxy-4'-methoxyacetophenone
Target: Calcium Channel
Atractylenolide III
T3902
Synonym: ICodonolactone,8β-Hydroxyasterolide
Target: Apoptosis
Bacopaside I
TN1420
Synonym:
Target: Others
Tenuifoliside B
T5702
Synonym:
Target: Dehydrogenase
Effusol
TN1601
Synonym:
Target: Caspase
L-Clausenamide
T32614
Synonym: (-)-Clausenamide
Target: Microtubule Associated
sn-Glycero-3-phosphocholine
T4439
Synonym: Choline Alfoscerate,Glycerophosphocholine,Glycerophosphorylcholine,Alpha-GPC,Choline glycerophosphate,L-α-GPC
Target: Endogenous Metabolite, AChE
(E)-3-(4-Methoxyphenyl)acrylic acid
T41095
Synonym:
Target: Glucosidase
Polygalacic acid
T3767
Synonym: Virgaureagenin G
Target: MMP, AChR, AChE
Orientin
T6S0721
Synonym: Lutexin,Luteolin-8-glucoside
Target: Others
2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid
T3011
Synonym: Kynurenine,Dl-Kynurenine,Kynurenin,3-Anthraniloylalanine
Target: Others, Endogenous Metabolite
Acetyl-L-carnitine hydrochloride
T2563
Synonym: Acetyl L-carnitine hydrochloride,O-Acetylcarnitine,O-acetyl-L-carnitine,O-Acetyl-L-carnitine hydrochloride
Target: Others, Endogenous Metabolite
Obtusifolin
T4S0969
Synonym:
Target: Antioxidant, NF-κB
Galactose
T0591L
Synonym: alpha-D-Galactose
Target:
Isorosmanol
TN1798
Synonym:
Target: Beta Amyloid, AChR
Esculin sesquihydrate
T80631
Synonym:
Target: p38 MAPK
Suffruticosol A
T81072
Synonym:
Target:
Feralolide
T79963
Synonym:
Target:
Guvacine ethyl ester
TJS0123
Synonym: PT00442-2,Arecoline
Target: Others

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-00381 PSMA Protein, Human, Recombinant (His) Human HEK293
Glutamate carboxypeptidase 2, also known as Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, Prostate-specific membrane antigen, GCPII, PSMA, FOLH1, and NAALAD1, is a single-pass type II membrane prote...
TMPK-00191 PILRA Protein, Mouse, Recombinant (hFc) Mouse HEK293
Alzheimer's disease (AD) is a neurodegenerative disease characterized by a progressive decline in cognitive performance; Mild Cognitive Impairment (MCI) is instead an objective decline in cognitive performance that does ...
TMPH-00223 Alpha-S2-casein Protein, Bovine, Recombinant (His & KSI) Bovine E. coli
SUCLG2 has a sensitivity of 75% and a specificity of 80% to distinguish follicular carcinoma from follicular adenoma PMID: 28709933 The absence of SUCLA2 and SUCLG2 in human glia is in compliance with the presence of alt...
TMPJ-01114 GAMT Protein, Human, Recombinant (His) Human E. coli
GAMT is a methyltransferase which belongs to the class I-like SAM-binding methyltransferase superfamily. It contains one RMT2 (arginine N-methyltransferase 2-like) domain and is expressed in liver. GAMT converts guanidoa...
TMPH-02150 SUCLG2 Protein, Human, Recombinant (His & SUMO) Human E. coli
SUCLG2 has a sensitivity of 75% and a specificity of 80% to distinguish follicular carcinoma from follicular adenoma PMID: 28709933 The absence of SUCLA2 and SUCLG2 in human glia is in compliance with the presence of alt...
TMPH-03025 VlpE Protein, Mycoplasma hyorhinis, Recombinant (His & Myc) Mycoplasma hyorhinis E. coli
Substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins, such as MEIS2 (Probable). Normal degradatio...
TMPY-04318 GRIK2 Protein, Human, Recombinant (hFc) Human HEK293
GRIK2 (Glutamate Ionotropic Receptor Kainate Type Subunit 2, also known as GluR6) is a Protein Coding gene. The GRIK2 (one of the kainate receptors) gene resides in a genetic linkage region (6q21) associated with bipolar...
TMPY-02547 IL-1RAPL1 Protein, Mouse, Recombinant (hFc) Mouse HEK293
Interleukin-1 receptor accessory protein-like 1 (IL1RAPL1) is a member of the interleukin-1 receptor family. The protein structurally comprises three extracellular immunoglobulin domains, which presumably mediate binding...
TMPY-01036 IL-1RAPL1 Protein, Human, Recombinant (His) Human HEK293
Interleukin-1 receptor accessory protein-like 1 (IL1RAPL1) is a member of the interleukin-1 receptor family. The protein structurally comprises three extracellular immunoglobulin domains, which presumably mediate binding...
TMPY-04033 FGF-14 Protein, Canine, Recombinant Canine E. coli
FGF14 is a member of the fibroblast growth factor (FGF) family. Members of this family possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic deve...
TMPY-02374 LSAMP Protein, Human, Recombinant (hFc) Human HEK293
The limbic system-associated membrane protein (LAMP) is a cell surface glycoprotein expressed by cortical and subcortical regions of the mammalian CNS that comprise or receive direct projections from limbic system struct...
TMPY-00985 IL-1RAPL1 Protein, Human, Recombinant (hFc) Human HEK293
Interleukin-1 receptor accessory protein-like 1 (IL1RAPL1) is a member of the interleukin-1 receptor family. The protein structurally comprises three extracellular immunoglobulin domains, which presumably mediate binding...
TMPY-02383 LSAMP Protein, Human, Recombinant (His) Human HEK293
The limbic system-associated membrane protein (LAMP) is a cell surface glycoprotein expressed by cortical and subcortical regions of the mammalian CNS that comprise or receive direct projections from limbic system struct...
TMPY-02804 FGF-14 Protein, Human, Recombinant (isoform 1B) Human E. coli
FGF14 is a member of the fibroblast growth factor (FGF) family. Members of this family possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic deve...
TMPY-05269 PSMA Protein, Human, Recombinant (His), Biotinylated Human HEK293
Glutamate carboxypeptidase 2, also known as Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, Prostate-specific membrane antigen, GCPII, PSMA, FOLH1, and NAALAD1, is a single-pass type II membrane prote...
TMPY-01390 PSMA Protein, Mouse, Recombinant (His) Mouse HEK293
Glutamate carboxypeptidase 2, also known as Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, Prostate-specific membrane antigen, GCPII, PSMA, FOLH1, and NAALAD1, is a single-pass type II membrane prote...
TMPY-06960 PSMA Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Glutamate carboxypeptidase 2, also known as Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, Prostate-specific membrane antigen, GCPII, PSMA, FOLH1, and NAALAD1, is a single-pass type II membrane prote...
PSMA Protein, Human, Recombinant (His)
TMPY-00381
Species: Human
Expression System: HEK293
PILRA Protein, Mouse, Recombinant (hFc)
TMPK-00191
Species: Mouse
Expression System: HEK293
Alpha-S2-casein Protein, Bovine, Recombinant (His & KSI)
TMPH-00223
Species: Bovine
Expression System: E. coli
GAMT Protein, Human, Recombinant (His)
TMPJ-01114
Species: Human
Expression System: E. coli
SUCLG2 Protein, Human, Recombinant (His & SUMO)
TMPH-02150
Species: Human
Expression System: E. coli
VlpE Protein, Mycoplasma hyorhinis, Recombinant (His & Myc)
TMPH-03025
Species: Mycoplasma hyorhinis
Expression System: E. coli
GRIK2 Protein, Human, Recombinant (hFc)
TMPY-04318
Species: Human
Expression System: HEK293
IL-1RAPL1 Protein, Mouse, Recombinant (hFc)
TMPY-02547
Species: Mouse
Expression System: HEK293
IL-1RAPL1 Protein, Human, Recombinant (His)
TMPY-01036
Species: Human
Expression System: HEK293
FGF-14 Protein, Canine, Recombinant
TMPY-04033
Species: Canine
Expression System: E. coli
LSAMP Protein, Human, Recombinant (hFc)
TMPY-02374
Species: Human
Expression System: HEK293
IL-1RAPL1 Protein, Human, Recombinant (hFc)
TMPY-00985
Species: Human
Expression System: HEK293
LSAMP Protein, Human, Recombinant (His)
TMPY-02383
Species: Human
Expression System: HEK293
FGF-14 Protein, Human, Recombinant (isoform 1B)
TMPY-02804
Species: Human
Expression System: E. coli
PSMA Protein, Human, Recombinant (His), Biotinylated
TMPY-05269
Species: Human
Expression System: HEK293
PSMA Protein, Mouse, Recombinant (His)
TMPY-01390
Species: Mouse
Expression System: HEK293
PSMA Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06960
Species: Human
Expression System: HEK293
Cat No. Product Name
L9840 Anti-Alzheimer's Disease Compound Library

1040 compounds
A unique collection of 1040 compounds with anti-AD activities or acting on main drug targets of AD can be used for HTS and HCS.
L3300 Histamine & Melatonin Receptor-Targeted Compound Library

155 compounds
A unique collection of 155 compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS) for new drugs;
L2630 Neuronal Differentiation Compound Library

680 compounds
680 compounds related to neuronal differentiation, suitable for the drug development of nervous system disease.
TargetMol