Shopping Cart
- Remove All
Your shopping cart is currently empty
SSR180711 hydrochloride
🥰Excellent
Catalog No. T28856Cas No. 446031-79-4
Alias SSR-180711C HCl, SSR-180711A HCl, SR-180711 HCl
SSR180711 hydrochloride (SSR-180711A HCl) is a selective Alpha7 nicotinic acetylcholine partial agonist for the study of neurodegenerative and cognitive disorders.
SSR180711 hydrochloride
🥰Excellent
Purity: 99.77%
Catalog No. T28856Alias SSR-180711C HCl, SSR-180711A HCl, SR-180711 HClCas No. 446031-79-4
SSR180711 hydrochloride (SSR-180711A HCl) is a selective Alpha7 nicotinic acetylcholine partial agonist for the study of neurodegenerative and cognitive disorders.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | 28 € | In Stock | |
| 5 mg | 63 € | In Stock | |
| 10 mg | 107 € | In Stock | |
| 25 mg | 178 € | In Stock | |
| 50 mg | 271 € | In Stock | |
| 1 mL x 10 mM (in DMSO) | 70 € | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "SSR180711 hydrochloride"
Adiphenine hydrochloride
Spasnil, Sentiv, Patrovina, Adiphenine HCl
T007250-42-0
Adiphenine hydrochloride (Patrovina), a nicotinic receptor inhibitor, can be used as an antispasmodic drug.
- 37 €
Size
QTY
Ribavirin
Cited
Tribavirin, RTCA, NSC-163039, ICN-1229
T068436791-04-5
Ribavirin (Tribavirin) is a synthetic nucleoside analog of ribofuranose with activity against hepatitis C virus and other RNA viruses.
- 37 €
Size
QTY
CitedCholine chloride
Hepacholine, Biocoline, Biocolina
T103967-48-1
Choline chloride (Biocoline) is a basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.
- 31 €
Size
QTY
Propoxur
Propoxure, Baygon, Aprocarb
T0976114-26-1
Propoxur (Propoxure) is an insecticide used to control cockroaches, flies, mosquitoes, and lawn and turf insects. Acute (short-term) exposure of humans to propoxur by ingestion leads to cholinesterase inhibition of red blood cells, with mild cholinergic symptoms including blurred vision, nausea, vomiting, sweating, and tachycardia; however, the effects are transient. Chronic (long-term) inhalation exposure has resulted in depressed cholinesterase levels, headaches, vomiting, and nausea in humans. Chronic ingestion studies in animals have reported depressed cholinesterase levels, depressed body weight, effects to the liver and bladder, and a slight increase in neuropathy. No information is available on the reproductive, developmental, or carcinogenic effects of propoxur in humans. Mixed results are available from cancer studies of propoxur in animals. EPA has not classified propoxur for carcinogenicity.
- 27 €
Size
QTY
Nanofin
Naniopinum, Lupetidine, Lupetidin, 2,6-Lupetidine, 2,6-Dimethylpiperidine
T1007504-03-0
Nanofin (Lupetidine) is a neuropathic blocker, with antihypertensive effect.
- 29 €
Size
QTY
Clozapine N-Oxide
Cited
T449434233-69-7
Clozapine N-oxide is the major metabolite of Clozapine and is blood-brain barrier permeable. Clozapine N-oxide is an agonist of DREADDs and activates the DREADD receptors hM3Dq and hM4Di. Clozapine N-oxide is also a dopamine antagonist and selective muscarinic M4 receptor agonist.
- 28 €
Size
QTY
CitedPilocarpine nitrate Cited
Pilofrin, Pilagan
T1231148-72-1
Pilocarpine nitrate (Pilagan) is a slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
- 38 €
Size
QTY
CitedForskolin Cited
FSK, Colforsin, Coleonol
T293966575-29-9
Forskolin (Coleonol) is a natural product, an adenylate cyclase activator (EC50=0.5 μM). Forskolin increases cAMP levels, activates PXR and FXR, and induces autophagy. Forskolin produces positive inotropic effects in the heart, and has platelet anticoagulant and antihypertensive effects.
- 34 €
Size
QTY
CitedPilocarpine Hydrochloride Cited
Pilocarpine HCl, NSC 5746 HCl, (+)-Pilocarpine hydrochloride
T080454-71-7
Pilocarpine Hydrochloride (NSC 5746 HCl) , a nonselective muscarinic acetylcholine receptor agonist, is utilized to produce an experimental model of epilepsy.
- 51 €
Size
QTY
CitedAmitriptyline hydrochloride
Tryptizol, Domical, Annoyltin, Amitriptyline HCl
T0678549-18-8
Amitriptyline hydrochloride (Annoyltin) is the hydrochloride salt of the tricyclic dibenzocycloheptadiene amitriptyline with antidepressant and antinociceptive activities.
5-HT ReceptorAChRAdrenergic ReceptorHistamine ReceptorNorepinephrineSerotonin TransporterSigma receptorSodium ChannelTrk receptor
- 42 €
Size
QTY
(+)-Sparteine
Pachycarpine
T7853492-08-0
(+)-Sparteine ​​is a quinoline alkaloid extracted from Scotch broom, a sodium channel blocker and a class 1a antiarrhythmic agent. It competitively inhibits the activity of nicotinic acetylcholine receptors in nerve cells and is a ganglionic blocking agent.
- 39 €
Size
QTY
Olanzapine Cited
LY170053
T1567132539-06-1
Olanzapine (LY170053) is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness.
- 28 €
Size
QTY
CitedSelect Batch
Purity:99.77%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | SSR180711 hydrochloride (SSR-180711A HCl) is a selective Alpha7 nicotinic acetylcholine partial agonist for the study of neurodegenerative and cognitive disorders. |
| Targets&IC50 | α7 nAChR (human):14 nM (Ki), α7 nAChR (human):18 nM, α7 nAChR (rat):22 nM (Ki), α7 nAChR (rat):30 nM |
| Alias | SSR-180711C HCl, SSR-180711A HCl, SR-180711 HCl |
| Molecular Weight | 361.66 |
| Formula | C14H18BrClN2O2 |
| Cas No. | 446031-79-4 |
| Smiles | Cl.Brc1ccc(OC(=O)N2CCN3CCC2CC3)cc1 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 30 mg/mL (82.95 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
| |||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy SSR180711 hydrochloride | purchase SSR180711 hydrochloride | SSR180711 hydrochloride cost | order SSR180711 hydrochloride | SSR180711 hydrochloride chemical structure | SSR180711 hydrochloride formula | SSR180711 hydrochloride molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.