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SSR180711 hydrochloride

Catalog No. T28856Cas No. 446031-79-4
Alias SSR-180711C HCl, SSR-180711A HCl, SR-180711 HCl

SSR180711 hydrochloride (SSR-180711A HCl) is a selective Alpha7 nicotinic acetylcholine partial agonist for the study of neurodegenerative and cognitive disorders.

SSR180711 hydrochloride

SSR180711 hydrochloride

Purity: 99.77%
Catalog No. T28856Alias SSR-180711C HCl, SSR-180711A HCl, SR-180711 HClCas No. 446031-79-4
SSR180711 hydrochloride (SSR-180711A HCl) is a selective Alpha7 nicotinic acetylcholine partial agonist for the study of neurodegenerative and cognitive disorders.
Pack SizePriceAvailabilityQuantity
1 mg$30In Stock
5 mg$67In Stock
10 mg$113In Stock
25 mg$188In Stock
50 mg$286In Stock
1 mL x 10 mM (in DMSO)$74In Stock
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Purity:99.77%
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Product Introduction

Bioactivity
Description
SSR180711 hydrochloride (SSR-180711A HCl) is a selective Alpha7 nicotinic acetylcholine partial agonist for the study of neurodegenerative and cognitive disorders.
Targets&IC50
α7 nAChR (rat):30 nM, α7 nAChR (rat):22 nM (Ki), α7 nAChR (human):18 nM, α7 nAChR (human):14 nM (Ki)
AliasSSR-180711C HCl, SSR-180711A HCl, SR-180711 HCl
Chemical Properties
Molecular Weight361.66
FormulaC14H18BrClN2O2
Cas No.446031-79-4
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 30 mg/mL (82.95 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.7650 mL13.8251 mL27.6503 mL138.2514 mL
5 mM0.5530 mL2.7650 mL5.5301 mL27.6503 mL
10 mM0.2765 mL1.3825 mL2.7650 mL13.8251 mL
20 mM0.1383 mL0.6913 mL1.3825 mL6.9126 mL
50 mM0.0553 mL0.2765 mL0.5530 mL2.7650 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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