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Pratensein
🥰Excellent
Catalog No. TN2100Cas No. 2284-31-3
Pratensein as a novel transcriptional up-regulator of scavenger receptor class B type I in HepG2 cells.
Pratensein
🥰Excellent
Purity: 99.72%
Catalog No. TN2100Cas No. 2284-31-3
Pratensein as a novel transcriptional up-regulator of scavenger receptor class B type I in HepG2 cells.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $193 | In Stock | |
| 5 mg | $480 | In Stock | |
| 10 mg | $687 | In Stock | |
| 25 mg | $1,080 | In Stock | |
| 50 mg | $1,480 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $490 | In Stock |
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Purity:99.72%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Pratensein as a novel transcriptional up-regulator of scavenger receptor class B type I in HepG2 cells. |
| In vitro | Protective effect of five isoflavones (formononetin, daidzein, Pratensein, calycosin and irilone) from Trifolium pratense on lipopolysaccharide-induced dopaminergic neurodegeneration was studied for the first time. The results showed that all five isoflavones attenuated LPS-induced decrease in dopamine uptake and the number of dopaminergic neurons in a dose-dependent manner in rat mesencephalic neuron-glia cultures. Moreover, they also significantly inhibited LPS-induced activation of microglia and production of tumor necrosis factor-alpha, nitric oxide and superoxide in mesencephalic neuron-glia cultures and microglia-enriched cultures. In addition, the rank order of protective potency of five isoflavones was: Pratensein>daidzein>calycosin>formononetin>irilone. |
| Molecular Weight | 300.26 |
| Formula | C16H12O6 |
| Cas No. | 2284-31-3 |
| Smiles | COc1ccc(cc1O)-c1coc2cc(O)cc(O)c2c1=O |
| Relative Density. | 1.512g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (166.52 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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