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ITI-214 is a picomolar PDE1 inhibitor with excellent selectivity against other PDE family members and against a panel of enzymes, receptors, transporters, and ion channels, exhibits potent PDE1 inhibitory activity (Ki = 58 pM).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $68 | In Stock | |
2 mg | $98 | In Stock | |
5 mg | $169 | In Stock | |
10 mg | $318 | In Stock | |
25 mg | $562 | In Stock | |
50 mg | $790 | In Stock | |
100 mg | $1,120 | In Stock | |
1 mL x 10 mM (in DMSO) | $229 | In Stock |
Description | ITI-214 is a picomolar PDE1 inhibitor with excellent selectivity against other PDE family members and against a panel of enzymes, receptors, transporters, and ion channels, exhibits potent PDE1 inhibitory activity (Ki = 58 pM). |
Targets&IC50 | PDE1:58 pM (Ki ) |
Alias | ITI214 |
Molecular Weight | 605.56 |
Formula | C29H29FN7O5P |
Cas No. | 1642303-38-5 |
Smiles | O=C(C1=C(NC2=CC=CC=C2)N(CC3=CC=C(C4=NC(F)=CC=C4)C=C3)N=C1N56)N(C)C5=N[C@@]7([H])[C@]6([H])CCC7.O=P(O)(O)O |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | DMSO: 30 mg/mL (49.54 mM) | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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