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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $41 | In Stock | |
5 mg | $97 | In Stock | |
10 mg | $163 | In Stock | |
25 mg | $363 | In Stock | |
50 mg | $543 | In Stock | |
100 mg | $783 | In Stock | |
500 mg | $1,620 | In Stock | |
1 mL x 10 mM (in DMSO) | $94 | In Stock |
Description | A-582941 dihydrochloride (A 582941) is a Selective agonist of α7 nAChR partial |
In vivo | A-582941 was found to exhibit high-affinity binding and partial agonism at alpha7 nAChRs.?In vitro and in vivo studies indicated that A-582941 activates signaling pathways known to be involved in cognitive function such as ERK1/2 and CREB phosphorylation.?A-582941 enhanced cognitive performance in behavioral models that capture domains of working memory, short-term recognition memory, memory consolidation, and sensory gating deficit.?A-582941 exhibited a benign secondary pharmacodynamic and tolerability profile as assessed in a battery of assays of cardiovascular, gastrointestinal, and CNS function. |
Alias | A 582941 |
Molecular Weight | 353.29 |
Formula | C17H22Cl2N4 |
Cas No. | 848591-90-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 55 mg/ml (196.17 mM) ![]() | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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