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SKF 81297 hydrobromide
🥰Excellent
Catalog No. T23361Cas No. 67287-39-2
Alias SKF81297 hydrobromide
SKF 81297 hydrobromide is a selective agonist of the dopamine D1-like receptor, with a high affinity for both D1 and D5 subtypes (Ki = 1.9 nM). SKF 81297 hydrochloride exhibits central activity in vivo and is widely used to study the neuromodulatory effects of the dopamine system, particularly in studies related to cognitive function and motor activity, such as Parkinson's disease.
SKF 81297 hydrobromide
🥰Excellent
Purity: 99.52%
Catalog No. T23361Alias SKF81297 hydrobromideCas No. 67287-39-2
SKF 81297 hydrobromide is a selective agonist of the dopamine D1-like receptor, with a high affinity for both D1 and D5 subtypes (Ki = 1.9 nM). SKF 81297 hydrochloride exhibits central activity in vivo and is widely used to study the neuromodulatory effects of the dopamine system, particularly in studies related to cognitive function and motor activity, such as Parkinson's disease.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $168 | In Stock | |
| 5 mg | $416 | In Stock | |
| 10 mg | $618 | In Stock | |
| 25 mg | $985 | In Stock | |
| 50 mg | $1,280 | In Stock | |
| 100 mg | $1,930 | In Stock | |
| 200 mg | $2,590 | In Stock |
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CitedSelect Batch
Purity:99.52%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | SKF 81297 hydrobromide is a selective agonist of the dopamine D1-like receptor, with a high affinity for both D1 and D5 subtypes (Ki = 1.9 nM). SKF 81297 hydrochloride exhibits central activity in vivo and is widely used to study the neuromodulatory effects of the dopamine system, particularly in studies related to cognitive function and motor activity, such as Parkinson's disease. |
| In vivo | SKF 81297 hydrobromide (0.05-0.3 mg/kg, intramuscularly) can stimulate MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) to impair motor behavior in monkeys. [1] |
| Alias | SKF81297 hydrobromide |
| Molecular Weight | 370.67 |
| Formula | C16H17BrClNO2 |
| Cas No. | 67287-39-2 |
| Smiles | Br.ClC=1C(O)=C(O)C=C2C1CCNCC2C=3C=CC=CC3 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | store under nitrogen,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | Ethanol: 1 mg/mL (2.7 mM), Sonication is recommended. DMF: 20 mg/mL (53.96 mM), Sonication is recommended. DMSO: 20 mg/mL (53.96 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
Ethanol/DMF/DMSO
DMF/DMSO
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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